Results 91 to 100 of about 221,261 (299)
Science & Society, 2002 In December 1999 two papers were published on the theme of inequality in journals of the American Economic Association. The first article (Welch, American Economic Review) celebrates inequality's recent advances in conventional neoliberal fashion, as an essentially progressive force that spawns innovation and stimulates growth. The second article (
openaire +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Siep STUURMAN, François Poulain de la Barre and the Invention of Modern Equality, Cambridge (Mass.), Harvard University Press, 2004, x-361 pages. [PDF]
, 2006 Marie-Frédérique Pellegrin +1 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Divided We Stand. American Workers and the Struggle for Black Equality By N
, 2003 Joseph A. McCartin
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Equality within Our Lifetimes [PDF]
, 2023 Jody Heymann, Aleta Sprague, Amy Raub
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Nordic Journal of Comparative and International EducationFrom a sociology of education perspective, a concern in teacher education is that teaching practices and expectations to the professional role of teachers often build on assumptions that derive from the social context of instruction.
Susan Wiksten
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source