Results 111 to 120 of about 208,965 (298)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Gender Bias in Clinical Trials of Sodium–Glucose Cotransporter 2 Inhibitors for the Treatment of Type 2 Diabetes Mellitus: A Systematic Review

Journal of Diabetes Research
Conclusions: Although the proportion of women included in iSGLT2 CTs seems acceptable, gender bias persists in the analysis of variables and in the study authors.
Santiago José Lora-Escobar, Lupe Rodríguez-de Francisco, Manuel López-Feijoo, Bernardo Santos-Ramos, Virginia Bellido, Rosa Casado-Mejía, Héctor Acosta-García   +6 more
doaj   +1 more source

Correction Note: Correction to "On Tests of Equality of Two Covariance Matrices" [PDF]

, 1968
N. Giri
openalex   +1 more source

Equal contribution means that the contribution is equal [PDF]

Swiss Medical Weekly, 2021
openaire   +3 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Pathways between childhood trauma, intimate partner violence, and harsh parenting: findings from the UN Multi-country Study on Men and Violence in Asia and the Pacific

The Lancet Global Health, 2017
Summary: Background: Although childhood trauma and violence against women are global public health issues, few population-based data from low-income and middle-income countries exist about the links between them.
Emma Fulu, DrPhD, Stephanie Miedema, MA, Tim Roselli, BSc, Sarah McCook, MA, Ko Ling Chan, PhD, Regine Haardörfer, PhD, Rachel Jewkes, ProfMBBS MD, Emma Fulu, Rachel Jewkes, Xian Warner, Stephanie Miedema, Tim Roselli, James Lang, Ruchira Tabassum Naved, Hamidul Huque, Subrina Farah, Muhammad Mizanur Rashid Shuvra, Arthur Erken, Wang Xiangxian, Fang Gang, Li Hongtao, Zeljka Mudrovcic, Wen Hua, Arie Hoekman, Elina Nikulainen, Bernard Coquelin, Mariam Khan, Wenny Kusuma, Clara Magariño Manero, Freya Larsen, Emma Fulu, Xian Warner, Saba Moussavi, Neloufer de Mel, Pradeep Peiris, Shyamala Gomez, Social Indicator Team, Kamani Jinadasa, Rachel Jewkes, Yandisa Sikweyiya, Nwabisa Shai, Francesca Drapuluvik-Tinabar, Peterson Magoola, Anthony Agyenta, Thomas Shanahan, Tracy Vienings, Rachel Jewkes, Claudia Garcia-Moreno, Ruchira Tabassum Naved, Kamani Jinadasa, Tracy Vienings, Wenny Kusuma, Rachel Jewkes, Raewyn Connell, Gary Barker, Alan Greig, Rahul Roy, Ravi Verma, Kalyani Menon Sen, Scott Johnson   +59 more
doaj  

Geologic map of the Equality quadrangle, western Kentucky [PDF]

, 1969
Gus H. Goudarzi
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Temperature coefficent of rf permeability measurement using an impedance bridge as an equality indicating device

, 1966
A. L. Rasmussen
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source