Results 111 to 120 of about 80,149 (308)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Estimating the size and composition of the lesbian, gay and bisexual population in Britain. Research Report 37 [PDF]

, 2009
The University of Kent was commissioned by the Equality and Human Rights Commission (the Commission) in November 2008 to investigate ways of measuring the lesbian, gay and bisexual population (LGB) of Great Britain (GB), for which there is no currently ...
Aspinall, Peter J.
core  

An Evaluation of Parents’ Foreign Language Teacher Choices in terms of Gender

Sakarya Üniversitesi Kadın Araştırmaları Dergisi
Parents are the first role models of their children and have the potential to affect children’s perceptions regarding gender. The present study aims to investigate parents' perceptions of gender equality and to see whether their perceptions of gender ...
Pınar Ketancı, Melek Kaymaz Mert
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

International insights: Equality in education

, 2019
Educational institutions should offer a safe and secure environment for young people. Part of that should be educational equity, which is a measure of achievement, fairness, and opportunity in education.
Chiou, Vana, Ertürk, Nesrin, Holz, Oliver, Shelton, F.   +3 more
core  

Parent–Child Dyadic Synchrony, Prosocial and Aggressive Behavior with Peers, and Friendship Quality in Early Adolescence

Psychology International
The present study examined the contribution of mother–child and father–child synchrony to early adolescents’ prosocial and aggressive behavior with peers and friendship quality.
Eric W. Lindsey
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Domain-based conceptual model to measure Gender Equality in Academia

, 2016
In this book we address the problem of measuring gender equality in Academia with the aim to define and develop a system of gender equality indicators (Unipd-Gei) in Universities and Research Institutions.
MANGANELLI, ANNA MARIA, ROCCO, ILARIA, PERINI, LORENZA, BADALONI, SILVANA   +3 more
core  

Equality

, 2017
This chapter examines the grounds of legislative review under the general constitutional guarantee of the right to equality as embodied in Article 14 of the Indian Constitution.
Tarunabh Khaitan
core   +1 more source

Gender Equality in the Romanian Local Public Institutions

Transylvanian Review of Administrative Sciences, 2011
Gender equality in public institutions is a sensitive topic considering the vast efforts of European countries to overcome the problems raised by gender inequality, gender segregation and gender discrimination in the labor market.
Sorin Dan ŞANDOR, Felicia Cornelia MACARIE, Simona Claudia CREŢA   +2 more
doaj