Results 31 to 40 of about 43,552 (298)

From a Common Principle of Equality to European Antidiscrimination Law

open access: yes, 2010
The principle of equality is an important part of the contemporary constitutional law of all European countries. It is therefore a common principle, and was, as such, also integrated in the legal system of the European Communities.
DE WITTE, Bruno
core   +2 more sources

The principle of equality as a challenge to the democratic rule of law the constitutional idea of equality

open access: yesZeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
In legal science, the constitutional idea of equality is considered from two perspectives: formal and material. Proper realisation and protection of this constitutional value, therefore, involves not only the requirement to apply the law in accordance ...
Anna Chorążewska
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Equality, Legal Certainty and Tax Legislation in the Netherlands<br>Fundamental Legal Principles as Checks on Legislative Power: A Case Study

open access: yesUtrecht Law Review, 2013
Fundamental legal principles may function as a check on legislative power protecting citizens against arbitrary interferences with their liberty. This contribution deals with the principle of equality and the principle of certainty. First, the testing of
Hans Gribnau
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Ekonomik Kamu Düzeninin Korunmasına Yönelik Kamu İhale Hukuku İlkeleri (Rekabet / Eşitlik / Kaynakların Verimli Kullanılması İlkeleri)

open access: yesAnadolu Üniversitesi Hukuk Fakültesi Dergisi, 2021
Kamu düzeni devletin varlığını idame ettirebilmesi bakımından önem arz etmektedir. Bireylerin sağlıklı, huzurlu ve güvenli bir şekilde yaşamaları durumunu ifade eden kamu düzeni, ekonomik kamu düzenini de içine alan geniş bir kavramdır.
Adem Avcı
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

CONSIDERATIONS ON THE PRINCIPLE OF EQUALITY IN EUROPEAN LEGISLATION [PDF]

open access: yesChallenges of the Knowledge Society, 2022
Among the numerous issues and wishes that mankind faces in general, the fundamental rights and duties of an individual hold a major place. The inclusion of citizens’ rights and liberties among the most important issues represents not only the result of ...
Daniel FLOREA
doaj  

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