Results 41 to 50 of about 43,552 (298)

Sovereign Inequality and Struggles for Equality

, 2023
The principle of sovereign equality is a “structural” or “systemic” prin-ciple that is devoid in itself of any specific legal content. It simply refers to the absence within the international legal system of any legal authority above the states, apart ...
Carlo Focarelli
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Rule of Law and the Principle of Equality Before the Law: Theory and Its Manifestation in Indonesia

Jurnal Idea Hukum
The rule of law and the principle of equality before the law require the lives of the nation and state without arbitrariness and discrimination. The state constitution should provide protection to citizens; in judicial practice, it turns out that not a ...
Ismail Marzuki
doaj   +1 more source

Substantive Equality and Jordan’s Principle: Challenges and Complexities

, 2021
This article examines the conceptual and procedural aspects of substantive equality with respect to Jordan’s Principle—a child-first principle intended to ensure First Nations children have equitable access to public services in Canada.
Jamieson, Gabriella, Sheppard, Colleen, Gunnarsson, Maya, Chadwick, Kathryn, Sinha, Vandna   +4 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

An introductory profile of the principle of equality

Nóema, 2011
Premessi brevi cenni storici sulla formulazione del principio d’eguaglianza, con particolare riferimento alle Costituzioni della Rivoluzione francese, l’A. esamina alcune questioni affrontate dalla Corte costituzionale italiana in relazione all’art.
Riccardo Conte
doaj   +1 more source

Equality and Heteronormativity. Heterosexual Majority and Homosexual Minority in the European Convention on Human Rights

, 2023
The European Convention on Human Rights protects equality through the principle of non-discrimination. However, this approach currently leads to insufficient results to achieve full equality in matters relating to sexual orientation.
Giulio Fedele
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The theological-ethical implications of Galatians 3:28 for a Christian perspective on equality as a foundational value in the human rights discourse

In die Skriflig, 2019
This article considers equality as a constitutional value from a Christian perspective. In view of the current questions about equality in the emerging post-secular paradigm, the specific aim of this study is to ascertain the relevance of Galatians 3:28 ...
Jakobus M. Vorster
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source