Results 71 to 80 of about 15,614,023 (261)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Communication-efficient and quantum-resistant PKE with multi-ciphertexts equality test
Amid the rapid evolution of cloud computing, safeguarding data privacy has become a core priority for both academic and industrial communities. To protect user data from unauthorized access, vast volumes of sensitive information are encrypted before ...
Tongchen Shen +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A SIMPLE BUT EFFICIENT SCHEME FOR COLOUR IMAGE RETRIEVAL BASED ON STATISTICAL TESTS OF HYPOTHESIS [PDF]
This paper proposes a simple but efficient scheme for colour image retrieval, based on statistical tests of hypothesis, namely test for equality of variance, test for equality of mean. The test for equality of variance is performed to test the similarity
K. Seetharaman, T. Hemalatha
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Association of lichen planus with dyslipidemia: A comparative, cross-sectional study
Context: Lichen planus (LP) is an idiopathic T-cell-mediated inflammatory disorder. Chronic inflammation may result in derangement of lipid metabolism. Some studies have shown that prevalence of dyslipidemia is more among patients with LP, whereas other ...
Neema Azeez, Neelakandhan Asokan
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Local culture-based education has an important role in character building for students. In a scientific heritage, there are values of wisdom that can be applied in everyday life.
Mawardy As Ary Putra
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

