Results 91 to 100 of about 6,503,562 (275)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Predication and equation [PDF]

open access: yes, 2013
English is one language where equative sentences and non-equative sentences have a similar surface syntax (but see Heggie 1988 and Moro 1997 for a discussion of more subtle differences).
Adger, David, Ramchand, Gillian
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Contextualización de las ecuaciones para la estimación de la estatura a partir de la hemibraza en una población santiaguera

open access: yesMedisan
Se realizó un estudio descriptivo y transversal de 265 adultos (101 hombres y 164 féminas) de la Facultad de Medicina No. 1 de Santiago de Cuba, desde septiembre hasta octubre del 2014, con vistas a determinar las ecuaciones para la estimación de la ...
Miguel Enrique Sánchez Hechavarría   +4 more
doaj  

Nonlinear differential equation with first order partial derivatives

open access: yesВестник КазНУ. Серия математика, механика, информатика, 2018
The asymptotic behavior of solutions of a nonlinear differential equation with first-order partial derivatives solved with respect to one of the derivatives is investigated.
T. М. Aldibekov, M. M. Aldazharova
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Heteroclinic Orbits for a Discrete Pendulum Equation [PDF]

open access: yes, 2010
About twenty years ago, Rabinowitz showed firstly that there exist heteroclinic orbits of autonomous Hamiltonian system joining two equilibria. A special case of autonomous Hamiltonian system is the classical pendulum equation.
Xiao, Huafeng, Yu, Jianshe
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

THE ACTION OF PERIODIC VARIABLE FORCES IN TIME ON AN ELASTIC MEDIUM [PDF]

open access: yesJournal of Research and Innovation for Sustainable Society, 2020
This paper solves the problems of the dynamics of thin-walled bar frames of open sections excited externally parametrically, decomposing the functions of the section displacements in time, after the bending functions in the main planes of inertia and ...
Nicoleta Maria MIHUT   +3 more
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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