Results 61 to 70 of about 173,503,456 (301)
Superfield continuous spin equations of motion
Physics Letters B, 2019 We propose a description of manifestly supersymmetric continuous spin representations in 4D,N=1 Minkowski superspace at the level of equations of motions.
I.L. Buchbinder +2 more
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
InfrastructuresThe AASHTO Manual for Assessing Safety Hardware (MASH) replaced the NCHRP Report 350 in 2009, becoming the new standard for evaluating safety hardware devices, including concrete bridge parapets; all new permanent installations of bridge rails on the ...
Bao Chuong, Ramesh B. Malla
doaj +1 more source
Mathematical and computer simulation of nonlinear free vibrations of elastic shallow shells with step-variable thickness [PDF]
Инженерно-строительный журнал, 2010 Shells as building elements are widely used in various fields of engineering. For example, in industrial and civil construction they are used as roofs and ceilings for structures with large spans (circuses, markets, railway stations, warehouses and ...
V.M. Zhgoutov
doaj
Journal of Applied Mathematics, 2013 We use a nonlinear transformation method to develop equivalent equations of motion of nonlinear homogeneous oscillatory systems with linear and nonlinear odd damping terms.
Alex Elías-Zúñiga +1 more
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Механика машин, механизмов и материалов, 2013 The mathematical model of multi-walled carbon nanotube embedded in an elastic matrix is proposed. The effect of the surrounding elastic medium are considered using the Winkler-type spring constant. The tube may be prestressed by external forces.
G.I. Mikhasev, A.N. Sheiko
doaj
Exploring complete positivity in hierarchy equations of motion [PDF]
, 2016 We derive a purely algebraic framework for the identi cation of hierarchy equations of motion that induce completely positive dynamics and demonstrate the applicability of our approach with several examples.
Rudnicki, L +3 more
core +1 more source