Results 41 to 50 of about 2,075 (185)

Varicellovirus UL49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]

, 2008
Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Danijela Koppers-Lalic, Marieke C. Verweij, Andrea D. Lipińska, Ying Wang, Edwin Quinten, Eric A. Reits, Joachim Koch, Sandra Loch, Marisa Marcondes Rezende, Franz Daus, Krystyna Bieńkowska-Szewczyk, Nikolaus Osterrieder, Thomas C. Mettenleiter, Mirjam H. M. Heemskerk, Robert Tampé, Jacques J. Neefjes, Shafiqul I. Chowdhury, Maaike E. Ressing, Frans A. M. Rijsewijk, Emmanuel J. H. J. Wiertz, Bill Sugden, JW Yewdell, BN Lilley, MT Vossen, R Abele, R Abele, PM van Endert, N Garbi, N Garbi, DR Peaper, J Koch, D Koppers-Lalic, A Hill, K Fruh, K Ahn, R Tomazin, B Galocha, L Neumann, C Aisenbrey, K Ahn, H Hengel, PJ Lehner, EW Hewitt, A Halenius, C Kyritsis, PG Stevenson, JM Boname, L Lybarger, PG Stevenson, YY Yu, JM Boname, X Wang, JM Boname, X Wang, X Wang, X Wang, AD Hislop, BC Barnett, AJ Davison, DJ McGeoch, M Mach, A Jons, AD Lipinska, J Rudolph, SX Wu, A Abendroth, JI Cohen, AJ Eisfeld, B Park, B Park, AP Ambagala, AP Ambagala, D Koppers-Lalic, S Uebel, TH Meyer, JJ Neefjes, S Gorbulev, EA Reits, BG Klupp, N Osterrieder, T van Hall, CN Garcia-Borges, S Loch, GE Dugan, D Koppers-Lalic, SI Chowdhury, SI Chowdhury, A Jons, JM Blevitt, A Al Mubarak, S Schrodt, J Koch   +91 more
core   +4 more sources

Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]

, 2019
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda, Barnum, Samantha, Delwart, Eric, Deng, Xutao, Li, Yanpeng, Pusterla, Nicola, Sabino-Santos, Gilberto, Sawaswong, Vorthon   +7 more
core   +1 more source

Occurrence of primary lymphocytic hypophysitis in two horses and presence of scattered T-lymphocytes in the normal equine pituitary gland [PDF]

, 2017
The postmortem examination of a 14-year-old Appaloosa gelding with clinically diagnosed pituitary pars intermedia dysfunction showed a unique finding of moderate multifocal lymphocytic hypophysitis (LH).
de Brot, Simone, Grau-Roma, Llorenc, Paton, Jacqui, Peckham, Robert, Stahel, Anina   +4 more
core   +1 more source

Equid herpesvirus 8: Complete genome sequence and association with abortion in mares.

PLoS ONE, 2018
Equid herpesvirus 8 (EHV-8), formerly known as asinine herpesvirus 3, is an alphaherpesvirus that is closely related to equid herpesviruses 1 and 9 (EHV-1 and EHV-9).
Marie Garvey, Nicolás M Suárez, Karen Kerr, Ralph Hector, Laura Moloney-Quinn, Sean Arkins, Andrew J Davison, Ann Cullinane   +7 more
doaj   +1 more source

A point mutation in a herpesvirus polymerase determines neuropathogenicity. [PDF]

PLoS Pathogens, 2007
Infection with equid herpesvirus type 1 (EHV-1) leads to respiratory disease, abortion, and neurologic disorders in horses. Molecular epidemiology studies have demonstrated that a single nucleotide polymorphism resulting in an amino acid variation of the
Laura B Goodman, Arianna Loregian, Gillian A Perkins, Josie Nugent, Elizabeth L Buckles, Beatrice Mercorelli, Julia H Kydd, Giorgio Palù, Ken C Smith, Nikolaus Osterrieder, Nicholas Davis-Poynter   +10 more
doaj   +1 more source

Molecular Surveillance of EHV-1 Strains Circulating in France during and after the Major 2009 Outbreak in Normandy Involving Respiratory Infection, Neurological Disorder, and Abortion

Viruses, 2019
Equine herpesvirus 1 (EHV-1) is an Alphaherpesvirus infecting not only horses but also other equid and non-equid mammals. It can cause respiratory distress, stillbirth and neonatal death, abortion, and neurological disease. The different forms of disease
Gabrielle Sutton, Marie Garvey, Ann Cullinane, Marion Jourdan, Christine Fortier, Peggy Moreau, Marc Foursin, Annick Gryspeerdt, Virginie Maisonnier, Christel Marcillaud-Pitel, Loïc Legrand, Romain Paillot, Stéphane Pronost   +12 more
doaj   +1 more source

Immediate early protein of equid herpesvirus type 1 as a target for cytotoxic T-lymphocytes in the thoroughbred horse [PDF]

, 2014
Cytotoxic T-lymphocytes (CTLs) are associated with protective immunity against disease caused by equid herpesvirus type 1 (EHV-1). However, the EHV-1 target proteins for CTLs are poorly defined.
Allen, Arvin, Bettina Wagner, Douglas F. Antczak, Jean-Christophe Audonnet, Julia H. Kydd, Julius Minke, Ruth Case, Sadzot-Delvaux, Splitter, Wills, Zhang   +11 more
core   +2 more sources

Autophagy in cultured murine neurons infected with equid herpesvirus 1

Acta virologica, 2014
In this study we investigated the relationship of equid herpesvirus 1 (EHV-1) infection to autophagy in primary culture of murine neurons. Infection with both Jan-E and Rac-H strains of EHV-1 resulted in the formation of autophagosomes in the cytoplasm during early stages of infection, while in late stages of infection autophagosomes were mainly ...
J, Cymerys, D, Miszczak, A, Słońska, A, Golke, M W, Bańbura   +4 more
openaire   +3 more sources

Genomic and phylogenetic analysis of Argentinian Equid Herpesvirus 1 strains

Virus Genes, 2008
Equid Herpesvirus 1 (EHV-1) has long been causally implicated in the occurrence of abortion, neonatal death, respiratory disease, and neurological disorders in horses. This study analyzed for the first time the characteristics of the genomic section of Argentinian EHV-1 strains and reconstructed the phylogeny in order to establish their origin.
Martín Ocampos, Giselle Paula, Fuentealba, Nadia Analía, Sguazza, Guillermo Hernán, Jones, Leandro Roberto, Cigliano, María Marta, Barbeito, Claudio Gustavo, Galosi, Cecilia Mónica   +6 more
openaire   +4 more sources

Deletion of the ORF2 gene of the neuropathogenic equine herpesvirus type 1 strain Ab4 reduces virulence while maintaining strong immunogenicity [PDF]

, 2018
Background Equine herpesvirus type 1 (EHV-1) induces respiratory infection, abortion, and neurologic disease with significant impact. Virulence factors contributing to infection and immune evasion are of particular interest.
Babasyan, Susanna, Freer, Heather, Osterrieder, Nikolaus, Perkins, Gillian, Rollins, Alicia, Schnabel, Christiane L., Wagner, Bettina, Watts, Christina, Wimer, Christine L.   +8 more
core   +1 more source