Results 91 to 100 of about 1,494,483 (312)

Entropy Alternatives for Equilibrium and Out-of-Equilibrium Systems

Entropy
We introduce a novel entropy-related function, non-repeatability, designed to capture dynamical behaviors in complex systems. Its normalized form, mutability, has been previously applied in statistical physics as a dynamical entropy measure associated with any observable stored in a sequential file.
Eugenio E. Vogel, Francisco José Peña, Gonzalo Saravia, Patricio Vargas   +3 more
openaire   +4 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

On Equilibrium Fluctuations

Tellus A: Dynamic Meteorology and Oceanography, 2022
This paper considers a dynamical system described by a multidimensional state vector x. A component 'x' of x evolves according to 'dx/dt = f'(x). Equilibrium fluctuations are fluctuations of an equilibrium solution x('t') obtained when the system is in its equilibrium state reached under a constant external forcing.
openaire   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

All non-Gaussian states are advantageous for channel discrimination: robustness of non-convex continuous variable quantum resources

New Journal of Physics
Which quantum phenomena are advantageous for information processing tasks? By classifying quantum states and operations as resourceful versus non-resourceful, or free, the mathematical formalism of quantum resource theories helps to address such ...
Leah Turner, Mădălin Guţă, Gerardo Adesso   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

pre-equilibrium (prior equilibrium) [PDF]

, 2014
Citation: 'pre-equilibrium (prior equilibrium)' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04810 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire   +1 more source

Neural correlates of vestibular adaptation in cosmonauts after long duration spaceflight

npj Microgravity
Long-duration spaceflight affects otolith-mediated ocular counter-roll (OCR) and brain function, but the relationship between these changes is unclear.
Catho Schoenmaekers, Steven Jillings, Sepehr Mortaheb, Dmitrii Glukhikh, Ivan Naumov, Elena Tomilovskaya, Ilya Rukavishnikov, Ekaterina Pechenkova, Alexandra Ryabova, Lyudmila Makovskaya, Inna Nosikova, Peter zu Eulenburg, Floris L. Wuyts   +12 more
doaj   +1 more source

Posturography table is a good test to evaluate the anterior cruciate Ligament reconstruction?

Orthopaedic Journal of Sports Medicine, 2019
Introduction: The success of anterior cruciate ligament reconstruction (ACLR) is assessed using subjective and functional scores, as well as measurements of knee laxity.
Frank Wein, Laetitia Peultier, Didier Mainard, Philippe Perrin   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source