Results 41 to 50 of about 1,696,755 (291)

Temperature control in molecular dynamic simulations of non-equilibrium processes [PDF]

, 2010
Thermostats are often used in various condensed matter problems, e.g. when a biological molecule undergoes a transformation in a solution, a crystal surface is irradiated with energetic particles, a crack propagates in a solid upon applied stress, two ...
Dawid Toton, Christian D Lorenz, Nikolaos Rompotis, Natalia Martsinovich, Lev Kantorovich, Allen M P, Barry P R, De Vita A, Trevethan T, Zwanzig R, Kantorovich L N Trevethan T Polesel-Maris J Martsinovich N Foster A, Soler J M, Iler R K, Frenkel D, Voter A F   +14 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Equilibrium Control of Robot Arm Tip Mounted on a Transfer Coaxial Two-Wheel Robot

Jurnal Nasional Teknik Elektro, 2023
Japan has continued to experience population decline which adversely affect working-age group (15-64 years). As a remedy to this social issue, advancements in robotics and human-machine cooperation is proposed to make up for the declining labor force ...
Toshiharu Yasui, Minoru Sasaki, Kojiro Matsushita, Joseph Muguro, Waweru Njeri, Titus Mulembo   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modulating crystal plane orientation to enhance the ablation resistance of lanthanum-tungsten cathode for magnetoplasmadynamic thruster

Journal of Materials Research and Technology
The tungsten cathode of the magnetoplasmadynamic thruster (MPDT) is a critical component that determines the long-term stability of the power system. The plasma environment causes significant ablation of the tungsten cathode due to its relatively high ...
Xinwei Zhang, Cheng Zhou, Xiaocai Ke, He Wang, Ge Wang, Zhimao Yang, Yong Li, Chuncai Kong   +7 more
doaj   +1 more source

Random Access Game and Medium Access Control Design [PDF]

, 2010
Motivated partially by a control-theoretic viewpoint, we propose a game-theoretic model, called random access game, for contention control. We characterize Nash equilibria of random access games, study their dynamics, and propose distributed algorithms (
Chen, Lijun, Doyle, John C., Low, Steven H.   +2 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

CONTROL OF THE DOUBLE INVERTED PENDULUM ON A CART USING THE NATURAL MOTION

Acta Polytechnica, 2013
This paper deals with controlling the swing-up motion of the double pendulum on a cart using a novel control. The system control is based on finding a feasible trajectory connecting the equilibrium positions from which the eigenfrequencies of the system ...
Zdenek Neusser, Michael Valášek
doaj   +1 more source

Control bifurcations [PDF]

, 2004
A parametrized nonlinear differential equation can have multiple equilibria as the parameter is varied. A local bifurcation of a parametrized differential equation occurs at an equilibrium where there is a change in the topological character of the ...
Chang, Dong Eui, Kang, Wei, Krener, Arthur J.   +2 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source