Results 41 to 50 of about 1,429,876 (274)

Dynamical environment in the vicinity of asteroids with an application to 41 Daphne

open access: yesResults in Physics, 2018
We studied the dynamical environment in the vicinity of the primary of the binary asteroid. The gravitational field of the primary is calculated by the polyhedron model with observational data of the irregular shape. The equilibrium points, zero-velocity
Yu Jiang
doaj   +1 more source

Homotopy Perturbation Method for Pneumonia–HIV Co-Infection

open access: yesFoundations, 2022
It is well known that HIV (human immunodeficiency virus) weakens the immune system of individuals, resulting in risk of other infections, such as pneumonia. The most frequent viral pneumonia seen in individuals infected with HIV is cytomegalovirus (CMV).
Nita H. Shah, Nisha Sheoran
doaj   +1 more source

Equilibrium points in n -person games [PDF]

open access: yesProceedings of the National Academy of Sciences, 1950
Soit un jeu à de \(n\) personnes, où chaque joueur possède un systeme fini de stratégies pures. Chacun d'entre eux ayant choisi une tactique de jeu, l'ensemble de ces tactiques constitute un \(n\)-uple de stratégies pures. A tout \(n\)-uple correspond un système défini de paiement entre les partenaires. L'A. considère chacun de ces \(n\)-uples comme un
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modeling and Analyzing Homogeneous Tumor Growth under Virotherapy

open access: yesMathematics, 2023
We present a mathematical model based on ordinary differential equations to investigate the spatially homogeneous state of tumor growth under virotherapy.
Chayu Yang, Jin Wang
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Investigating the Effects of a Fractional Operator on the Evolution of the ENSO Model: Bifurcations, Stability and Numerical Analysis

open access: yesFractal and Fractional, 2023
Recent years have seen an increase in scientific interest in the El Nio/La Nia Southern Oscillation (ENSO), a quasiperiodic climate phenomenon that takes place throughout the tropical Pacific Ocean over five years and causes significant harm.
Yuqi Zhang   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analyzing Stability of Equilibrium Points in Neural Networks: A General Approach

open access: yes, 2003
Networks of coupled neural systems represent an important class of models in computational neuroscience. In some applications it is required that equilibrium points in these networks remain stable under parameter variations.
Chen, Yonghong   +3 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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