Results 41 to 50 of about 1,435,956 (282)

Equilibria of point charges on convex curves

open access: yes, 2015
We study the equilibrium positions of three points on a convex curve under influence of the Coulomb potential. We identify these positions as orthotripods, three points on the curve having concurrent normals. This relates the equilibrium positions to the
Khimshiashvili, Giorgi   +2 more
core   +1 more source

Nonlinear Stability in the Generalised Photogravitational Restricted Three Body Problem with Poynting-Robertson Drag [PDF]

open access: yes, 2007
The Nonlinear stability of triangular equilibrium points has been discussed in the generalised photogravitational restricted three body problem with Poynting-Robertson drag.
A. Deprit   +24 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dynamical environment in the vicinity of asteroids with an application to 41 Daphne

open access: yesResults in Physics, 2018
We studied the dynamical environment in the vicinity of the primary of the binary asteroid. The gravitational field of the primary is calculated by the polyhedron model with observational data of the irregular shape. The equilibrium points, zero-velocity
Yu Jiang
doaj   +1 more source

Virtual Testing of Experimental Continuation [PDF]

open access: yes, 2018
We present a critical advance in experimental testing of nonlinear structures. Traditional quasi-static experimental methods control the displacement or force at one or more load-introduction points on a structure.
Groh, Rainer M. J.   +3 more
core   +3 more sources

Equilibrium points in n -person games [PDF]

open access: yesProceedings of the National Academy of Sciences, 1950
Soit un jeu à de \(n\) personnes, où chaque joueur possède un systeme fini de stratégies pures. Chacun d'entre eux ayant choisi une tactique de jeu, l'ensemble de ces tactiques constitute un \(n\)-uple de stratégies pures. A tout \(n\)-uple correspond un système défini de paiement entre les partenaires. L'A. considère chacun de ces \(n\)-uples comme un
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On an SEIR Epidemic Model with Vaccination of Newborns and Periodic Impulsive Vaccination with Eventual On-Line Adapted Vaccination Strategies to the Varying Levels of the Susceptible Subpopulation

open access: yesApplied Sciences, 2020
This paper investigates a susceptible-exposed-infectious-recovered (SEIR) epidemic model with demography under two vaccination effort strategies. Firstly, the model is investigated under vaccination of newborns, which is fact in a direct action on the ...
Malen Etxeberria-Etxaniz   +2 more
doaj   +1 more source

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