Results 71 to 80 of about 1,435,956 (282)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
MathematicsThis study numerically explores the dynamics of the photogravitational circular restricted three-body problem, where an infinitesimal particle moves under the gravitational influence of two primary bodies connected by a massless rod. These primary masses
Aguda Ekele Vincent +3 more
doaj +1 more source
Basins of convergence of equilibrium points in the generalized Hill problem
, 2017 The Newton-Raphson basins of attraction, associated with the libration points (attractors), are revealed in the generalized Hill problem. The parametric variation of the position and the linear stability of the equilibrium points is determined, when the ...
Zotos, Euaggelos E.
core +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Multiple Attractors for a Competitive System of Rational Difference Equations in the Plane
Abstract and Applied Analysis, 2011 We investigate global dynamics of the following systems of difference equations xn+1=β1xn/(B1xn+yn), yn+1=(α2+γ2yn)/(A2+xn), n=0,1,2,…, where the parameters β1, B1,
S. Kalabušić +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Advances in Mathematical Physics, 2012 This paper investigates the positions and linear stability of an infinitesimal body around the equilibrium points in the framework of the Robe’s circular restricted three-body problem, with assumptions that the hydrostatic equilibrium figure of the first
Jagadish Singh, Abubakar Umar Sandah
doaj +1 more source
A Mathematical Model of Black Rhino Translocation Strategy
Journal of Mathematical and Fundamental Sciences, 2015 A deterministic mathematical model of the black rhino population in South Africa will be discussed. The model is constructed by dividing the black rhino population into multiple patches.
Dipo Aldila +4 more
doaj +1 more source
Analyzing Stability of Equilibrium Points in Neural Networks: A General Approach
, 2003 Networks of coupled neural systems represent an important class of models in computational neuroscience. In some applications it is required that equilibrium points in these networks remain stable under parameter variations.
Chen, Yonghong +3 more
core +3 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source