Results 51 to 60 of about 219,775 (187)

The Differences in Histoarchitecture of Hoof Lamellae between Obese and Lean Draft Horses

Animals, 2022
Obesity is a common problem in horses. The associations between obesity and equine metabolic syndrome (EMS) and between EMS and laminitis are known. However, there is a lack of data on whether obesity itself can affect hoof lamellae.
Magdalena Senderska-Płonowska, Natalia Siwińska, Agnieszka Zak-Bochenek, Marta Rykała, Malwina Słowikowska, Jan P. Madej, Katarzyna Kaleta-Kuratewicz, Artur Niedźwiedź   +7 more
doaj   +1 more source

Effects of equine metabolic syndrome on inflammation and acute-phase markers in horses.

Domestic Animal Endocrinology, 2020
Obesity and metabolic disorders are associated with systemic low-grade chronic inflammation, both in humans and animals. The aim of the study is to assess the effects of obesity and hyperinsulinemia on individual components of the acute-phase reaction in
A. Żak, N. Siwińska, S. Elzinga, V. Barker, T. Stefaniak, B. Schanbacher, N. Place, A. Niedźwiedź, A. Adams   +8 more
semanticscholar   +1 more source

Influence of functional nutrients on insulin resistance in horses with equine metabolic syndrome [PDF]

Pakistan Veterinary Journal, 2014
The obesity is a rising health problem both in veterinary and human medicine. In equine medicine excessive body weight is frequently related to insulin resistance and laminitis as is defined as equine metabolic syndrome (EMS).
Krzysztof Marycz, Eberhard Moll and Jakub Grzesiak
doaj  

Obesity-Related Metabolic Dysfunction in Dairy Cows and Horses: Comparison to Human Metabolic Syndrome

Life, 2021
Obesity has become a serious health problem with frequent occurrence both in human and animal populations. It is estimated that it may affect over 85% of the human population and 70–80% of horses and cows by 2030.
Zsofia Daradics, Cristian M. Crecan, Mirela A. Rus, Iancu A. Morar, Mircea V. Mircean, Adriana Florinela Cătoi, Andra Diana Cecan, Cornel Cătoi   +7 more
doaj   +1 more source

Evaluation of Four Diagnostic Tests for Insulin Dysregulation in Adult Light‐Breed Horses

Journal of Veterinary Internal Medicine, 2016
Background Several tests have been evaluated in horses for quantifying insulin dysregulation to support a diagnosis of equine metabolic syndrome. Comparing the performance of these tests in the same horses will provide clarification of their accuracy in ...
L.K. Dunbar, K.A. Mielnicki, K.A. Dembek, R.E. Toribio, T.A. Burns   +4 more
doaj   +1 more source

Differential Proteomic Expression of Equine Cardiac and Lamellar Tissue During Insulin-Induced Laminitis

Frontiers in Veterinary Science, 2020
Endocrinopathic laminitis is pathologically similar to the multi-organ dysfunction and peripheral neuropathy found in human patients with metabolic syndrome.
Allison Campolo, Matthew W. Frantz, Melody A. de Laat, Melody A. de Laat, Steven D. Hartson, Martin O. Furr, Véronique A. Lacombe   +6 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Metabolic syndrome: is equine disease comparable to what we know in humans? [PDF]

Endocrine Connections, 2014
This review summarizes similarities and differences between the metabolic syndromes in humans and equines, concerning the anatomy, symptoms, and pathophysiological mechanisms. In particular, it discusses the structure and distribution of adipose tissue and its specific metabolic pathways.
Ertelt, Antonia, Barton, Ann Kristin, Schmitz, Robert, Gehlen, Heidrun   +3 more
openaire   +2 more sources

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source