Results 51 to 60 of about 758,479 (312)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Optimized power converters for electrically augmented on-orbit propulsion systems
, 2002 Advances in satellite thruster technology have produced the requirement for high power electrical supplies to operate electrically augmented on-orbit propulsion systems.
Olyniec, Lee Michael
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
ARBITRAL RESOLUTIONS OF COMMERCIAL LITIGATIONS IN THE LIGHT OF UNCITRAL MODEL LAW
Pravo, 2013 The author points out the importance of a quality arbitral process, particularly in commercial disputes. The author analyzes the solution of UNCITRAL Model Law and order regarding the appointment of arbitrators, their characteristics, powers and ...
Miladin Pejak
doaj
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
مدیریت اطلاعات سلامت, 2019 Introduction: Mammography is the cornerstone of breast cancer screening and early detection. This study was conducted to investigate the status of digital mammography facilities in Isfahan City, Iran, in terms of equipment and physical-quality ...
Mitra Momenzade +3 more
doaj +1 more source
Effects of a Combined Exercise Program Using an iPad for Older Adults [PDF]
Healthcare Informatics Research, 2016 ObjectivesThe purpose of this study was to examine the function, health status, and efficacy effects of a combined exercise program using an iPad among older women in Korea, a tech-savvy country.MethodsThe study employed a pretest and posttest ...
Juhee Lee +3 more
doaj +1 more source
Improvement of Tuberculosis Laboratory Capacity on Pemba Island, Zanzibar: A Health Cooperation Project. [PDF]
, 2012 Low-income countries with high Tuberculosis burden have few reference laboratories able to perform TB culture. In 2006, the Zanzibar National TB Control Programme planned to decentralize TB diagnostics.
Emanuele Nicastri +10 more
core +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source