Results 31 to 40 of about 237,518 (267)
Current approach for the prosthesis patient mismatch
Türk Kardiyoloji Derneği Arşivi, 2013 All prosthetic valves are at least mildly stenotic and have relatively high transvalvular pressure gradients that can be observed despite normal prosthesis function.
Asuman Biçer Yeşilay +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
EnergiesAs the key non-electric protection equipment of an oil-immersed transformer, the gas relay plays an important role in ensuring the safe operation of the transformer.
Yuangang Sun +6 more
doaj +1 more source
A 5-Month-Old Infant with Right Scrotum Swelling
Emergency, 2016 Case presentation:A five-month-old male infant (gestational age 28 weeks, birthweight 1020 gm) with posthemorrhagic hydrocephalus subsequent to prematurity had a left sided ventriculoperitoneal shunt 3 months after birth. Frontal radiography of the chest
Shih-Wen Hung +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modelling of Equipment Failure Rate Accounting for the Uncertainty [PDF]
International Journal on Smart Sensing and Intelligent Systems, 2015 Abstract A fuzzy model for failure rate with the consideration of the effects of uncertain factors in distribution reliability evaluation is presented. The possibility and credibility distribution analyzed on the basis of sample datum are used for quantifying effects of the uncertainty done to failure rate. Mathematically, the failure
Tian, H.X., Wu, W.F, Wang, P., Li, H.Z.
openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Frontiers in Energy Research, 2023 In recent years, with the development of new energy technology and the country’s strong support for electric vehicles, there is a lack of effective electric vehicle charging fault analysis and diagnosis methods at this stage.
Bin Zhu +4 more
doaj +1 more source