Results 71 to 80 of about 1,569,331 (368)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Modern weapons and military equipments for the issue 4-2021

open access: yesVojnotehnički Glasnik, 2021
Produženje životnog veka: Velika Britanija pokreće program modernizacije tenka Challenger 2. Ruska armija dobija samohodni protivtenkoski top Sprut-SDM1 SPATG. Francuska je odabrala nuklearni pogon za svoj budući nosač aviona.
Dragan M. Vučković
doaj  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Modern weapons and military equipments for issue 3-2020 / Современное вооружение и военное оборудование, к выпуску № 3-2020 / Savremeno naoružanje i vojna oprema za broj 3-2020

open access: yesVojnotehnički Glasnik, 2020
Modernization of the Moscow anti-missile shield; Turkey chooses Ukrainian active protection system Zaslon; New Swedish submarine; Firefly: Israeli "wandering" ammunition (or kamikaze drone); The MZ-204 Highlander mortar prototype is ready; Operation ...
Dragan M. Vučković
doaj  

Modern weapons and military equipments for issue 1-2019 / Современное вооружение и военное оборудование, к выпуску № 1-2019 / Savremeno naoružanje i vojna oprema za broj 1-2019 [PDF]

open access: yesVojnotehnički Glasnik, 2019
Characteristics of modern combat shoes / Характеристики современной боевой обуви / Karakteristike modernih borbenih ...
Miloš M. Jevtić
doaj  

Modern weapons and military equipment for the issue 2-2021

open access: yesVojnotehnički Glasnik, 2021
Tank dreams: Mulling the future of Russian armour design concepts; Elta Systems reveals new passive radar; Rafael demos Drone Dome-L with hard-kill laser capability; Eyes in the sky: How the Orlan-10 UAV is shaping Russian artillery operations;
Dragan M. Vučković
doaj  

A Sodium laser guide star coupling efficiency measurement method [PDF]

open access: yes, 2016
Large telescope's adaptive optics (AO) system requires one or several bright artificial laser guide stars to improve its sky coverage. The recent advent of high power sodium laser is perfect for such application.
Bian, Qi   +10 more
core   +2 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Discussion on Development of Ocean Exploration Technologies and Equipments

open access: yes, 2013
Firstly,strategic demands of ocean exploration technologies and equipments in four aspects are analyzed,including ocean exploitation and economic growth,maritime rights and interests maintenance and maritime security,construction of ocean ecological ...
Xinke Zhu   +5 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

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