Results 71 to 80 of about 1,618,905 (354)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Theoretical study on the sabot separation process of a sub-caliber projectile fired from rifled guns

open access: yesDefense and Security Studies
Sub-caliber projectiles have been widely used in modern warfare due to their ability to enhance accuracy and ballistic performance. For such projectiles, however, an effective separation of the penetrator from the sabot upon exiting the barrel is ...
Bui Xuan Son   +3 more
doaj   +1 more source

Knowledge modelling for integrating semantic web services in e-government applications [PDF]

open access: yes, 2005
Service integration and domain interoperability are the basic requirements in the development of current service-oriented e-Government applications. Semantic Web and, in particular, Semantic Web Service (SWS) technology aim to address these issues ...
Cabral, Liliana   +2 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Modern weapons and military equipments for the issue 4-2021

open access: yesVojnotehnički Glasnik, 2021
Produženje životnog veka: Velika Britanija pokreće program modernizacije tenka Challenger 2. Ruska armija dobija samohodni protivtenkoski top Sprut-SDM1 SPATG. Francuska je odabrala nuklearni pogon za svoj budući nosač aviona.
Dragan M. Vučković
doaj  

The measurement of dissolved oxygen today - tradition and topicality [PDF]

open access: yes, 2008
Today, the determination of the dissolved oxygen content of natural waters is practically an essential duty whenever background data is collected for investigations of a hydrobiological, ecological, and nature or environmental protection viewpoint.
Andrikovics, S.   +6 more
core  

Parametric optimization of the femoropopliteal artery stent design based on numerical analysis [PDF]

open access: yes, 2021
High-failure rates of Peripheral Arterial Disease (PAD) stenting were reported due to the inability of certain stent strut configuration to accommodate severe biomechanical environment of the Femoro-Popliteal Artery (FPA) such as bends, twists, and ...
Kareem, Ali Kamil
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

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