Results 101 to 110 of about 678,166 (300)

Méthodologie de l’élaboration du corpus multilingue de termes grammaticaux : notes introductives

open access: yesStudia Romanica Posnaniensia
The paper represents a continuation of previously conducted work and aims to explore the methodological aspects involved in developing a multilingual corpus of grammatical terminology. The languages included are Slovak, French, English, and Latin.
Daniel Vojtek
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Adult Equivalence Scales, Inequality and Poverty [PDF]

open access: yes
This paper examines the sensitivity of inequality and poverty measures to the adult equivalence scale and the unit of analysis. Comparisons are made using parametric equivalence scales, and income units include individuals, equivalent adults and ...
Catherine Sleeman, John Creedy
core  

Transfer Function of a Time-Varying Control System Considering Actuator Inertia

open access: yesChallenges and Issues of Modern Science
Purpose. Methodological support for building an algorithm for determining the transfer function (TF) of a link, which, considering the actuator dynamics and the disturbed motion of the mass center, is equivalent on a selected trajectory section to a ...
Volt Avdieiev
doaj  

Equivalence relations as an analysis criterion of scientific relevance of analytical categories

open access: yesActa Colombiana de Psicología, 2017
The aim of this paper is to propose equivalence relations as a structural criterion or analytical order, through which the functions of knowledge required in a scientific activity are delimited.
Tiberio Pérez Manrique   +1 more
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Loomis Type Theorem for Bounded Sequences

open access: yesAxioms
This paper extends Loomis’s classical spectral criterion for almost periodic functions to bounded sequences in discrete settings. We first establish a discrete Kadets-type theorem for bounded sequences by regarding almost periodic functions as continuous
Yuan-Yuan Chen   +2 more
doaj   +1 more source

Development of multi-criteria decision analysis (MCDA) framework for off-patent pharmaceuticals – an application on improving tender decision making in Indonesia

open access: yesBMC Health Services Research, 2018
Background Off-patent pharmaceuticals (OPPs) hold vital importance in meeting public health objectives, especially in developing countries where resources are limited.
Andras Inotai   +10 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy