Results 81 to 90 of about 678,166 (300)

Hypotetický důkaz v dialogu Menón

open access: yesReflexe, 2019
The paper focuses on the second geometrical proof in Plato’s Meno (86e4–87b2). Its purpose is to present the modern interpretations of the passage and to explore their implications for the philosophical reading of the dialogue as a whole.
Samuel Zajíček
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Letter to the Editor—Criterion Equivalence in Discrete Dynamic Programming [PDF]

open access: yesOperations Research, 1969
This note shows that for finite state-and-action-space Markovian decision processes, a policy is 1-optimal if and only if it is average overtaking optimal, so the two criteria are equivalent.
openaire   +2 more sources

Problem Gambling Study: Final Report

open access: yes, 1993
In March, 1993, Criterion Research Corp., in partnership with Dr. Rachel Volberg of Gemini Research, New York, was commissioned by the Manitoba Lotteries Foundation (MLF) to conduct a study to determine the prevalence of problem gambling in the ...
Manitoba Lotteries Foundation   +1 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

An Equivalent Statement to Nicolas' Criterion

open access: yes, 2015
Nicolas' criterion for the Riemann Hypothesis (RH) is an inequality based on primorials and the Euler totient function. The aim of this paper is to reformulate Nicolas' criterion and prove the equivalent statement. I will show that the reformulation is bounded and montonic using Chebyshev's function and results on prime numbers.
openaire   +2 more sources

Amenability, Countable Equivalence Relations, and Their Full Groups [PDF]

open access: yes, 2008
This thesis consists of an introduction and four independent chapters. In Chapter 1, we study homeomorphism groups of metrizable compactifications of the natural numbers. Those groups can be represented as almost zero-dimensional Polishable subgroups
Tsankov, Todor Dimitrov
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Horizontal Equity and Progession when Equivalence Scales are not Constant. [PDF]

open access: yes
Household needs must be taken into account when designing an equitable income tax. If the equivalence scale is income dependent it is not transparent how to achieve equity.
Peter J Lambert, Udo Ebert
core  

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