Results 141 to 150 of about 71,544 (304)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Limit of equivalence ratio on mixing enhancement near the tube exit in a tone excited rich flame
, 1997 An experimental investigation has been made with the objective of studying the limit of equivalent ratio (phi) on mixing enhancement in a tone excited jet rich flame.
Kim, JK, Shin, Hyun Dong
core +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Scalar structure of turbulent stratified swirl flames conditioned on local equivalence ratio
, 2016 © 2016 The Combustion Institute. In a recent paper (Kamal, et al., 2015), we reanalyzed single shot species and temperature measurements from non-swirling flames stabilized on the Cambridge/Sandia stratified burner by conditioning measurements on the ...
Kamal, MM, Barlow, R, Hochgreb, S, ,
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Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Response of heat release to equivalence ratio variations in high Karlovitz premixed H2/air flames at 20 atm [PDF]
, 2019 This paper presents three-dimensional direct numerical simulations of lean premixed H2/air flames with equivalence ratios 0.4, 0.5 and 0.6, respectively.
Wang, X, Jin, T, Luo, KH
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Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
Linearized reactive flow with equivalence ratio perturbations
, 2018 This thesis investigates a numerical method to quickly assess the response of a laminar, premixed flame to equivalence ratio perturbations. This linearized reacting flow (LRF) solver relies on linearizing Navier-Stokes equations with reacting species ...
Maximilian Kühn
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