Results 91 to 100 of about 4,548,219 (290)
Equivalence of two strong forms of determinacy [PDF]
Determinacy of all games of length ω \omega with moves from R {\mathbf {R}} is equivalent to determinacy of all games of length ω 2 {\omega ^2} with moves from ω \omega .
openaire +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
On a new discrete Mulholland-type inequality in the whole plane
A new discrete Mulholland-type inequality in the whole plane with a best possible constant factor is presented by introducing multi-parameters, applying weight coefficients, and using Hermite–Hadamard’s inequality.
Bicheng Yang, Qiang Chen
doaj +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
α-Connections and a Symmetric Cubic Form on a Riemannian Manifold
In this paper, we study the construction of α -conformally equivalent statistical manifolds for a given symmetric cubic form on a Riemannian manifold.
Keiko Uohashi
doaj +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Equivalent Forms of the Multivariate Portmanteau Statistic [PDF]
SUMMARY The Box-Pierce portmanteau test for univariate autoregressive moving-average (arma) time-series models has been generalized to multivariate time-series models by several authors, and several different definitions of the test statistic have resulted.
openaire +2 more sources
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source

