Results 1 to 10 of about 849,592 (288)

Versal deformations of a Dirac type differential operator

open access: yes, 1999
If we are given a smooth differential operator in the variable $x\in {\mathbb R}/2\pi {\mathbb Z},$ its normal form, as is well known, is the simplest form obtainable by means of the $\mbox{Diff}(S^1)$-group action on the space of all such operators.
Abraham R.   +7 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

On a compound approximation operator of D.D. Stancu type

open access: yesJournal of Numerical Analysis and Approximation Theory, 2006
In this note we consider a linear and positive compound approximation operator of D.D. Stancu type depending of several parameters; we give the expressions of this operator on the test functions, the conditions under which this operator converges to a ...
Maria Crăciun
doaj   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Spectral decomposition of self-adjoint operators in Pontryagin and Krein spaces

open access: yesСовременная математика: Фундаментальные направления
We consider a self-adjoint operator acting in a Krein space and possessing an invariant subspace that is maximal nonnegative and decomposes into a direct sum of a uniformly positive (i.e., equivalent to a Hilbert space with respect to the inner ...
V. A. Strauss
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Agrobacterium tumefaciens estC, Encoding an Enzyme Containing Esterase Activity, Is Regulated by EstR, a Regulator in the MarR Family. [PDF]

open access: yesPLoS ONE, 2016
Analysis of the A. tumefaciens genome revealed estC, which encodes an esterase located next to its transcriptional regulator estR, a regulator of esterase in the MarR family.
Surawach Rittiroongrad   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Boundedly solvable extensions of delay differential operators

open access: yesElectronic Journal of Differential Equations, 2017
We describe all boundedly solvable extensions of minimal operators generated by first-order linear delay differential operators in Hilbert spaces of vector-functions on finite intervals. Also, we study the structure of spectrum of these extensions.
Bahadir O. Guler   +2 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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