Results 61 to 70 of about 7,980,180 (293)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A reverse Mulholland-type inequality in the whole plane
Journal of Inequalities and Applications, 2018 We present a new reverse Mulholland-type inequality in the whole plane with a best possible constant factor by introducing multiparameters, applying weight coefficients, and using the Hermite–Hadamard inequality.
Jianquan Liao, Bicheng Yang
doaj +1 more source
On form-equivalence of deterministic pure grammar forms
Theoretical Computer Science, 1982 AbstractPure grammars are grammars without non-terminals. In this paper we show as one main result that any two acyclic deterministic pure (dP) grammars that generate the same finite language are isomorphic. Furthermore, the notion of a pure grammar form is investigated. As the second main result we show that the form-equivalence problem for dP grammar
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2022 The Precious Cornerstone University,2022/2023 JUPEB A'LEVEL APPLICATION form ☎️"08065912405" Post UTME/Direct Entry (DE) Screening/Admission Form ☎️ 08065912405 Dr GRACE General Requirements The minimum entry requirements for admission into Covenant ...
The Precious Cornerstone University,2022/2023 JUPEB A'LEVEL APPLICATION form ☎️"08065912405" Post UTME/Direct Entry (DE) Screening/Admission Form ☎️ 08065912405 Dr GRACE General Requirements The minimum entry requirements for admission into Covenant University are credit level passes in five (5) subjects at the SSCE/GCE O'Level/NECO or its equivalent, obtained at not more than two (2) sittings. The subjects passed must include English Language and Mathematics.
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source