Results 41 to 50 of about 3,440,905 (299)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Method for judging seismic stability state of soil slopes
Yantu gongcheng xuebao, 2018 Based on the strength reduction FEM, the method for judging the stability state of soil slopes under earthquake action is analyzed. The length ratio of equivalent plastic strain zone in the slope is defined, and the corresponding relationship between the
ZHANG Jiang-wei 1, LI Xiao-jun 2, WANG Xiao-ming 1, CHI Ming-jie 2, WANG Yu-shi 2
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Iteratively Decoded Irregular Variable Length Coding and Trellis Coded Modulation
, 2007 In this paper we propose a novel Irregular Variable Length Coding (IrVLC) scheme for near-capacity joint source and channel coding. We employ a number of Variable Length Coding (VLC) component codebooks having different coding rates for encoding ...
L-L. Yang +9 more
core +1 more source
工程科学学报, 2017 The effects of structural dimensions such as central tube equivalent radius, branch tube equivalent radius, tube spacing, and tube length on the performance of a flat double-P type radiant tube were studied in this paper. The structural dimensions of the
XU Qian, FENG Jun-xiao
doaj +1 more source
Self-Intersection Numbers of Length-Equivalent Curves on Surfaces [PDF]
Experimental Mathematics, 2014 Two free homotopy classes of closed curves in an orientable surface with negative Euler characteristic are said to be length equivalent if for any hyperbolic structure on the surface, the length of the geodesic in one class is equal to the length of the geodesic in the other class.
openaire +3 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
, 2018 Open constraints were introduced to model the many industrial applications in which a task can be handled by several resources. Open constraints are unique because the set of variables over which the the constraint is defined is a set-variable. Regin and
Pascal van Hentenryck (5457176) +4 more
core +1 more source
Applied Sciences, 2023 This study aimed to evaluate the subsurface drainage of a permeable friction course (PFC) via two-dimensional finite element analysis. To achieve the scope, PFCs with equivalent water flow paths of length values of 10, 15, 20, and 30 m and slope values ...
Thi My Dung Huynh +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source