Results 61 to 70 of about 2,847,969 (279)

Stretching rates and equivalent length near the tropopause [PDF]

Journal of Geophysical Research: Atmospheres, 2003
Diagnostics of mixing in the upper troposphere/lower stratosphere region reveal interesting seasonal and interannual variability and illustrate how the subtropical tropopause can be identified with a region of minimum mixing, a partial barrier to the transport of air between the troposphere and stratosphere.
Scott, R.-K., Shuckburgh, Emily, Cammas, Jean-Pierre, Legras, Bernard   +3 more
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The predictive accuracy of axial length to corneal curvature radius ratio for myopia in children and adolescents

Frontiers in Medicine
PurposeTo analyze the association of axial length to corneal curvature radius ratio (AL/CR) and other ocular biometric parameters with myopia in children and adolescents.MethodsA cross-sectional study was conducted among children and adolescents aged 6 ...
Lin Wang, Qianru Zhang, Changdong Liu, Changdong Liu, Qiqi Liu, Peipei Zhang   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Efficacy and Safety of Low-Concentration Atropine in Slowing Myopia Progression in Children in Japan: The Randomized, Double-Blind Phase II/III ORANGE Study

Ophthalmology Science
Purpose: To evaluate the efficacy and safety of low-concentration atropine ophthalmic solution for slowing disease progression in children with myopia and assessing rebound phenomenon after treatment cessation.
Kyoko Ohno-Matsui, MD, PhD, Tae Igarashi-Yokoi, MD, PhD, Yukie Migita, Yutaka Yamakawa, MSc   +3 more
doaj   +1 more source

Self-normalizing phase measurement in multimode terahertz spectroscopy based on photomixing of three lasers

, 2014
Photomixing of two near-infrared lasers is well established for continuous-wave terahertz spectroscopy. Photomixing of three lasers allows us to measure at three terahertz frequencies simultaneously.
A. Roggenbuck, E. Vidal, H. Schmitz, J. Hemberger, K. Thirunavukkuarasu, Lee Y. S., M. Grüninger, M. Langenbach   +7 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The relation between the geometric parameters of grinding powders grains measured by laser diffraction and light-microscopical methods

MATEC Web of Conferences, 2018
The studies were conducted on grinding powders of black silicon carbide with F180-F60 grit produced by Volzhsky Abrasive Plant. The length, width, perimeter, area and reduced diameter of the grain area were determined by light-microscopical method, the ...
Nosenko Vladimir A., Aleksandrov Alexey A.   +1 more
doaj   +1 more source