Results 41 to 50 of about 2,101,126 (257)

Riedizioni e riemissioni di periodici nel contesto editoriale italiano: XVII secolo-1805. Esempi e osservazioni

open access: yesTECA, 2011
The paper shows some ways of publishing Italian journals from XVII century to early years of ‘800. It contains large set of exemples of important titles issued again as monographics in context without ties with journalism yet; some reprints are also ...
Rudj Gorian
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

On problems of the lens of the eye radiation dose monitoring

open access: yesРадиационная гигиена, 2016
According to results of in-depth studies, the risk of the radiation-induced cataract is higher than it was considered earlier. In April 2011, ICRP released a statement on the tissue reactions.
G. N. Kaydanovsky, E. N. Shleenkova
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Monotone Picard Maps in Relational Metric Spaces

open access: yesMathematics
The 2008 fixed point result on rs-relational metric spaces due to Jachymski is equivalent with the classical 1922 Banach Contraction Principle. This is also valid for the 1961 statement in metric spaces due to Edelstein, or the 2005 fixed point result in
Mihai Turinici
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Statement of cash flows

open access: yes, 2014
Previous chapters presented the income statement, statement of comprehensive income, statement of changes in equity and balance sheet; this chapter introduces the statement of cash flows.
Maloney, Suzanne
core   +1 more source

On the density and the structure of the Peirce-like formulae [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2008
Within the language of propositional formulae built on implication and a finite number of variables $k$, we analyze the set of formulae which are classical tautologies but not intuitionistic (we call such formulae - Peirce's formulae).
Antoine Genitrini   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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