Results 41 to 50 of about 2,101,126 (257)
The paper shows some ways of publishing Italian journals from XVII century to early years of ‘800. It contains large set of exemples of important titles issued again as monographics in context without ties with journalism yet; some reprints are also ...
Rudj Gorian
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This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
On problems of the lens of the eye radiation dose monitoring
According to results of in-depth studies, the risk of the radiation-induced cataract is higher than it was considered earlier. In April 2011, ICRP released a statement on the tissue reactions.
G. N. Kaydanovsky, E. N. Shleenkova
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Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Monotone Picard Maps in Relational Metric Spaces
The 2008 fixed point result on rs-relational metric spaces due to Jachymski is equivalent with the classical 1922 Banach Contraction Principle. This is also valid for the 1961 statement in metric spaces due to Edelstein, or the 2005 fixed point result in
Mihai Turinici
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Previous chapters presented the income statement, statement of comprehensive income, statement of changes in equity and balance sheet; this chapter introduces the statement of cash flows.
Maloney, Suzanne
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On the density and the structure of the Peirce-like formulae [PDF]
Within the language of propositional formulae built on implication and a finite number of variables $k$, we analyze the set of formulae which are classical tautologies but not intuitionistic (we call such formulae - Peirce's formulae).
Antoine Genitrini +2 more
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Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

