The endoplasmic reticulum-associated degradation machinery selectively degrades stress-induced TIN1 during stress recovery. [PDF]
Wang Y +10 more
europepmc +1 more source
One Health horsepower in hemostasis: SEL1Lecting stable platelet adhesion. [PDF]
Schneider CD, Luyendyk JP.
europepmc +1 more source
Natural SEL1L variants rescue a model of NGLY1 deficiency and modify ERAD function and proteasome sensitivity. [PDF]
Tu'ifua TK, Chow CY.
europepmc +1 more source
A Novel Small-Molecule GRP94 Modulator Increases PCSK9 Secretion and Promotes LDLR Degradation. [PDF]
Yan W, Zhong Y, Fang S.
europepmc +1 more source
Hyperactive 20<i>S</i> proteasome enhances proteostasis and ERAD in <i>C. elegans</i> via degradation of intrinsically disordered proteins. [PDF]
Salcedo-Tacuma D +4 more
europepmc +1 more source
Death, taxes, and rhomboids: Understanding the ubiquitous roles of the rhomboid protein superfamily. [PDF]
Sawczyc H, Kosteletos S, Lange A.
europepmc +1 more source
SEL1L-HRD1-mediated ERAD in mammals. [PDF]
Wang HH, Biunno I, Sun S, Qi L.
europepmc +1 more source
Cryo-EM structure of the human Derlin-1/p97 complex reveals a hexameric channel in ERAD. [PDF]
Wang Q +9 more
europepmc +1 more source
The Race to Salvage Glucocerebrosidase: Understanding Small-Molecule Therapies for GBA1-Associated Parkinsonism. [PDF]
Henderson MJ +5 more
europepmc +1 more source
Endoplasmic Reticulum-Targeting Natural Compounds: A Novel Frontier in Alleviating Liver Fibrosis. [PDF]
Huang C +5 more
europepmc +1 more source

