Results 171 to 180 of about 186,336 (266)

Endogenous oestrogens as neuroprotective modulators in the human retina: Evidence from transcriptomic profiling and aromatase inhibition

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Single‐cell transcriptomics reveals that the human retina expresses a broad repertoire of steroid hormone biosynthesis and estrogen signalling genes. Functional validation in retinal explants shows that local estrogen synthesis is neuroprotective, preventing photoreceptor death and limiting microglial activation. Abstract Steroid hormones, particularly
Antolin Canto   +6 more
wiley   +1 more source

Marburg and Sudan viruses elicit divergent interferon responses and cytokine storm signaling in Egyptian rousette bat macrophages. [PDF]

open access: yesFront Immunol
Yordanova IA   +7 more
europepmc   +1 more source

Effect of Hormone Replacement Therapy on Liver and Cardiometabolic Outcomes in Peri‐Menopausal MASLD

open access: yesLiver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver disease globally. Menopause is associated with increased hepatic fat deposition and thus metabolic dysfunction, contributing to heightened risk of progressive liver and cardiovascular disease.
Alex E. Henney   +4 more
wiley   +1 more source

The historical evolution of the neurological examination. [PDF]

open access: yesArq Neuropsiquiatr
Esmanhotto BB   +4 more
europepmc   +1 more source

Ecological predictors of plant responses to sequential herbivory: a meta‐analysis

open access: yesNew Phytologist, Volume 250, Issue 2, Page 1128-1140, April 2026.
Summary Plants evolved alongside herbivores for over 400 million years and show remarkable plasticity in responses to attack by multiple herbivores. However, it is often debated which herbivore traits predict plant responses and it is poorly understood how plant life‐history traits contribute to the variation observed in plant responses.
Zoë Delamore   +2 more
wiley   +1 more source

Design, Synthesis, and Biological Evaluation of Efflux-Resistant Imatinib Derivatives. [PDF]

open access: yesJ Med Chem
Chowdhury MM   +7 more
europepmc   +1 more source

Impacts of exercise, renin–angiotensin system modulation or both on skeletal muscle circadian gene expression

open access: yesExperimental Physiology, Volume 111, Issue 4, Page 2086-2105, 1 April 2026.
Abstract Ageing negatively affects quality of life and healthspan, and interventions are needed to slow this progressive decline. Previously, we have demonstrated the potential functional benefits of combining a genetically modified probiotic (GMP) targeting the non‐canonical arm of the renin–angiotensin system (RAS) with exercise training.
Emily L. Zumbro   +8 more
wiley   +1 more source

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