Single‐cell transcriptomics reveals that the human retina expresses a broad repertoire of steroid hormone biosynthesis and estrogen signalling genes. Functional validation in retinal explants shows that local estrogen synthesis is neuroprotective, preventing photoreceptor death and limiting microglial activation. Abstract Steroid hormones, particularly
Antolin Canto +6 more
wiley +1 more source
Marburg and Sudan viruses elicit divergent interferon responses and cytokine storm signaling in Egyptian rousette bat macrophages. [PDF]
Yordanova IA +7 more
europepmc +1 more source
Effect of Hormone Replacement Therapy on Liver and Cardiometabolic Outcomes in Peri‐Menopausal MASLD
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver disease globally. Menopause is associated with increased hepatic fat deposition and thus metabolic dysfunction, contributing to heightened risk of progressive liver and cardiovascular disease.
Alex E. Henney +4 more
wiley +1 more source
The historical evolution of the neurological examination. [PDF]
Esmanhotto BB +4 more
europepmc +1 more source
Ecological predictors of plant responses to sequential herbivory: a meta‐analysis
Summary Plants evolved alongside herbivores for over 400 million years and show remarkable plasticity in responses to attack by multiple herbivores. However, it is often debated which herbivore traits predict plant responses and it is poorly understood how plant life‐history traits contribute to the variation observed in plant responses.
Zoë Delamore +2 more
wiley +1 more source
PREPARED STATEMENT [ "U.S.-European Economic Relations"] OF RICHARD D. ERB, Resident Fellow American EnterPrise Institute for Public Policy Research before the SUBCOMMITTEE ON EUROPE AND THE MIDDLE EAST COMMITTEE ON FOREIGN AFFAIRS U.S. HOUSE OF REPRESENTATIVES. WASHINGTON, D.C. 22 July 1980 [PDF]
Erb, Richard D.
core
Design, Synthesis, and Biological Evaluation of Efflux-Resistant Imatinib Derivatives. [PDF]
Chowdhury MM +7 more
europepmc +1 more source
Abstract Ageing negatively affects quality of life and healthspan, and interventions are needed to slow this progressive decline. Previously, we have demonstrated the potential functional benefits of combining a genetically modified probiotic (GMP) targeting the non‐canonical arm of the renin–angiotensin system (RAS) with exercise training.
Emily L. Zumbro +8 more
wiley +1 more source
Fertility preservation by ovarian tissue transportation and centralized cryobanking for a 20-year-old woman with Hodgkin lymphoma. [PDF]
Michaeli J +3 more
europepmc +1 more source

