Assessing transfer entropy from biochemical data [PDF]
We address the problem of evaluating the transfer entropy (TE) produced by biochemical reactions from experimentally measured data. Although these reactions are generally non-linear and non-stationary processes making it challenging to achieve accurate modeling, Gaussian approximation can facilitate the TE assessment only by estimating covariance ...
arxiv +1 more source
Towards Scalable Modeling of Biology in Event-B [PDF]
Biology offers many examples of large-scale, complex, concurrent systems: many processes take place in parallel, compete on resources and influence each other's behavior. The scalable modeling of biological systems continues to be a very active field of research.
arxiv
Uncovering the dynamic effects of DEX treatment on lung cancer by integrating bioinformatic inference and multiscale modeling of scRNA-seq and proteomics data [PDF]
Motivation: Lung cancer is one of the leading causes for cancer-related death, with a five-year survival rate of 18%. It is a priority for us to understand the underlying mechanisms that affect the implementation and effectiveness of lung cancer therapeutics.
arxiv
Prediction of Binding Affinity for ErbB Inhibitors Using Deep Neural Network Model with Morgan Fingerprints as Features [PDF]
The ErbB receptor family, including EGFR and HER2, plays a crucial role in cell growth and survival and is associated with the progression of various cancers such as breast and lung cancer. In this study, we developed a deep learning model to predict the binding affinity of ErbB inhibitors using molecular fingerprints derived from SMILES ...
arxiv
High-frequency transduction of c-erbB in avian leukosis virus-induced erythroblastosis [PDF]
B D Miles, Harriet L. Robinson
openalex +1 more source
Cell transformation by a virus containing a molecularly constructed gag-erbB fused gene [PDF]
S Kawai+3 more
openalex +1 more source
Creation of a chimeric oncogene: analysis of the biochemical and biological properties of v-erbB/src fusion polypeptide [PDF]
Martin L. Privalsky
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DETECTION OF EPIDERMAL GROWTH-FACTOR RECEPTOR AND C-ERBB-2 GENE AMPLIFICATION IN TRANSITIONAL-CELL BLADDER-CARCINOMA USING THE DIFFERENTIAL PCR TECHNIQUE [PDF]
Vassilis G. Gorgoulis+3 more
openalex +1 more source
C-ERBB-2 oncogens protein inIn situ and invasive lobular breast neoplasia [PDF]
Peggy L. Porter+4 more
openalex +1 more source
C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas. [PDF]
Jeffrey A. Kern+7 more
openalex +1 more source