Results 1 to 10 of about 7,906 (54)

Assessing transfer entropy from biochemical data [PDF]

open access: yesPhysical Review E 105, 034403 (2022), 2021
We address the problem of evaluating the transfer entropy (TE) produced by biochemical reactions from experimentally measured data. Although these reactions are generally non-linear and non-stationary processes making it challenging to achieve accurate modeling, Gaussian approximation can facilitate the TE assessment only by estimating covariance ...
arxiv   +1 more source

Towards Scalable Modeling of Biology in Event-B [PDF]

open access: yesarXiv, 2021
Biology offers many examples of large-scale, complex, concurrent systems: many processes take place in parallel, compete on resources and influence each other's behavior. The scalable modeling of biological systems continues to be a very active field of research.
arxiv  

Uncovering the dynamic effects of DEX treatment on lung cancer by integrating bioinformatic inference and multiscale modeling of scRNA-seq and proteomics data [PDF]

open access: yesarXiv, 2022
Motivation: Lung cancer is one of the leading causes for cancer-related death, with a five-year survival rate of 18%. It is a priority for us to understand the underlying mechanisms that affect the implementation and effectiveness of lung cancer therapeutics.
arxiv  

Prediction of Binding Affinity for ErbB Inhibitors Using Deep Neural Network Model with Morgan Fingerprints as Features [PDF]

open access: yesarXiv
The ErbB receptor family, including EGFR and HER2, plays a crucial role in cell growth and survival and is associated with the progression of various cancers such as breast and lung cancer. In this study, we developed a deep learning model to predict the binding affinity of ErbB inhibitors using molecular fingerprints derived from SMILES ...
arxiv  

C-ERBB-2 oncogens protein inIn situ and invasive lobular breast neoplasia [PDF]

open access: bronze, 1991
Peggy L. Porter   +4 more
openalex   +1 more source

C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas. [PDF]

open access: bronze, 1994
Jeffrey A. Kern   +7 more
openalex   +1 more source

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