Hypothalamic astroglial erbB tyrosine kinase receptors are required for the timely initiation of mammalian puberty. Ligand-dependent activation of these receptors sets in motion a glia-to-neuron signaling pathway that prompts the secretion of luteinizing
Anda Cornea +5 more
core +1 more source
GENERATION OF pFastBacl-HT AND ISOLATION OF ErbB-2, ErbB-3 AND ErbB-4 cDNAs by RT-PCR
Over-expression of the ErbB receptor tyrosine kinase subfamily has been implicated in various types of human cancers. In the current study, ErbB-2, ErbB-3, and ErbB-4 tyrosine kinase domain cDNAs were isolated by RT-PCR and subcloned into a pFastBac-HT ...
Diekhans, Stacy
core +1 more source
In cancer, vulnerable breast epithelium malignance tendency correlates with number and activation of ErbB receptor tyrosine kinases. In the presented work, we observe ErbB receptors activated by irradiation-induced DNA injury or neuregulin- 1 β ...
Ines Nesnidal +5 more
core +1 more source
Cytohesins are cytoplasmic ErbB receptor activators [PDF]
Signaling by ErbB receptors requires the activation of their cytoplasmic tyrosine kinase domains which is initiated by ligand binding to the receptor ectodomains.
Bill, Anke
core
Genomic alterations of ERBB receptors in cancer: clinical implications. [PDF]
Mishra R, Hanker AB, Garrett JT.
europepmc +1 more source
In vitro synergistic effect of AXL, FAK and ErbB receptors inhibitors for head and neck cancer. [PDF]
Lucarini V +15 more
europepmc +1 more source
Surface plasmon resonance microscopy reveals N-glycosylation driven modulation of affinity and avidity of ErbB receptors in whole single pancreatic cancer cells. [PDF]
Aguilar Díaz de León JS +2 more
europepmc +1 more source
Natural Products as Chemopreventive Agents by Potential Inhibition of the Kinase Domain in ErbB Receptors. [PDF]
Olivero-Acosta M +2 more
europepmc +1 more source
A Structural Insight Into Two Important ErbB Receptors (EGFR and HER2) and Their Relevance to Non-Small Cell Lung Cancer. [PDF]
Topalan E +8 more
europepmc +1 more source
Dacomitinib, a pan-inhibitor of ErbB receptors, suppresses growth and invasive capacity of chemoresistant ovarian carcinoma cells. [PDF]
Momeny M +21 more
europepmc +1 more source

