Results 21 to 30 of about 34,393 (185)
Frontiers in Molecular Neuroscience, 2018 Increasing evidence demonstrates that the neurotrophic factor Neuregulin 1 (NRG1) and its receptors, ErbB tyrosine kinases, modulate midbrain dopamine (DA) transmission.
Ada Ledonne +2 more
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ON THE NOTION OF SYNERGY OF MONOCLONAL ANTIBODIES AS DRUGS [PDF]
Biotechnologia Acta, 2013 History of developing synergy between monoclonal antibodies, anti-tumor activity of monoclonal antibodies against tyrosine-kinases receptors EGFR/ErbB-1 and HER2/ErbB-2 as well as growth factor VEGF in various combinations are considered in the article ...
Michael Sela
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Biomolecules, 2022 The cross-talk between axon and glial cells during development and in adulthood is mediated by several molecules. Among them are neurotransmitters and their receptors, which are involved in the control of myelinating and non-myelinating glial cell ...
Roberta Piovesana +5 more
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Identification of nucleolin as new ErbB receptors- interacting protein.
PLoS ONE, 2008 BackgroundThe ErbB receptor tyrosine kinases are major contributors to malignant transformation. These receptors are frequently overexpressed in a variety of human carcinomas.
Ayelet Di Segni +2 more
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Phosphotyrosine interactome of the ErbB‐receptor kinase family [PDF]
Molecular Systems Biology, 2005 Interactions between short modified peptide motifs and modular protein domains are central events in cell signal-transduction. We determined interaction partners to all cytosolic tyrosine residues of the four members of the ErbB-receptor family in an unbiased fashion by quantitative proteomics using pull-down experiments with pairs of phosphorylated ...
Schulze, W. X., Deng, L., Mann, Matthias
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Insights into the evolution of the ErbB receptor family and their ligands from sequence analysis
BMC Evolutionary Biology, 2006 Background In the time since we presented the first molecular evolutionary study of the ErbB family of receptors and the EGF family of ligands, there has been a dramatic increase in genomic sequences available. We have utilized this greatly expanded data
Staros James V, Stein Richard A
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Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis. [PDF]
PLoS ONE, 2010 The Lrig genes encode a family of transmembrane proteins that have been implicated in tumorigenesis, psoriasis, neural crest development, and complex tissue morphogenesis. Whether these diverse phenotypes reflect a single underlying cellular mechanism is
Victoria E Abraira +3 more
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EGFR Signaling in Lung Fibrosis
Cells, 2022 In this review article, we will first provide a brief overview of the ErbB receptor–ligand system and its importance in developmental and physiological processes.
Fabian Schramm +2 more
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Translocation of ErbB receptors into the nucleus [PDF]
Revista de Oncología, 2003 The work in the authors laboratory was financed by grants (to AV) from the Comisión Interministerial de Ciencia y Tecnología (SAF2002-03258), the Consejería de Educación de la Comunidad de Madrid (08.1/0027/2001-1), and the Agencia Española de Cooperación Internacional (2002CN0013).
Villalobo, Antonio +2 more
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Targeting the Calmodulin-Regulated ErbB/Grb7 Signaling Axis in Cancer Therapy
Journal of Pharmacy & Pharmaceutical Sciences, 2013 Signal transduction pathways essential for the survival and viability of the cell and that frequently present aberrant expression or function in tumors are attractive targets for pharmacological intervention in human cancers. In this short review we will
Antonio Villalobo +3 more
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