ErbB signaling in brain injury regeneration: Pathway interactions and therapeutic potential
The ErbB signaling network has recently emerged as a key modulator of central nervous system responses to injury. This review provides a comprehensive overview of ErbB receptors and their ligands, highlighting canonical and non-canonical signaling ...
Patricia Pérez-García +7 more
doaj +1 more source
Uterine Serous Carcinoma Arising From Endometrial Polyp: A Case Report
Serous carcinoma is the prototype of type II endometrial carcinoma. A 71-year-old woman who had history of smoking, diabetes mellitus and hypertension admitted to the hospital with postmenopausal uterine bleeding.
Sibel Bektaş +4 more
doaj
ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner
The different epidermal growth factor (EGF)-related peptides elicit a diverse array of biological responses as the result of their ability to activate distinct subsets of ErbB receptor dimers, leading to the recruitment of different intracellular ...
Graus-Porta, Diana +11 more
core +1 more source
Spinal nerve injury causes upregulation of ErbB2 and ErbB3 receptors in rat dorsal root ganglia
Satoshi Mizobuchi,1* Hirotaka Kanzaki,1–3* Hiroki Omiya,1 Yoshikazu Matsuoka,1 Norihiko Obata,1 Ryuji Kaku,1 Hirochika Nakajima,1 Mamoru Ouchida,2 Kiyoshi Morita11Department of Anesthesiology and Resuscitology, 2Department of Molecular Genetics,
Mizobuchi S +8 more
doaj
Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer
Udgivelsesdato: 2008-MayErbB receptors (EGFR (ErbB1), ErbB2, ErbB3, and ErbB4) are important regulators of normal growth and differentiation, and they are involved in the pathogenesis of cancer.
Kirstine Roepstorff +9 more
core +1 more source
Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma. [PDF]
Meyers N +3 more
europepmc +1 more source
Targeting ErbB Receptors in High-Grade Glioma.
High-grade gliomas, including glioblastoma, are among the most malignant and treatment-refractory human neoplasms. The tumors show high levels of resistance to conventional therapies (i.e.
Berezowska, S;Schlegel, J
core
Genomic alterations of ERBB receptors in cancer: clinical implications. [PDF]
Mishra R, Hanker AB, Garrett JT.
europepmc +1 more source
In vitro synergistic effect of AXL, FAK and ErbB receptors inhibitors for head and neck cancer. [PDF]
Lucarini V +15 more
europepmc +1 more source
Surface plasmon resonance microscopy reveals N-glycosylation driven modulation of affinity and avidity of ErbB receptors in whole single pancreatic cancer cells. [PDF]
Aguilar Díaz de León JS +2 more
europepmc +1 more source

