Results 91 to 100 of about 84,102 (243)

Long‐Read Pan‐Cancer Transcriptomics Unravel Distinct Alteration Trends Between Gene and Isoform Expression in Tumorigenesis

iMetaMed, EarlyView.
Long‐read profiling of 144 tumor‐normal pairs identifies isoform‐level cancer dysregulation independent of gene changes. Our scoring system prioritizes isoform‐driven prognostic genes across cancers. ABSTRACT Tumorigenesis involves transcriptomic alterations at both gene and isoform levels.
Yuying Ding, Bo Wu, Dan Zhou, Qiang Li, Dingru Li, Mengyun Cai, Zhiyan Chen, Caimei Zhong, ChuanLe Xiao, Yuhua Deng   +9 more
wiley   +1 more source

Geospace Exploration Project: Arase (ERG) [PDF]

, 2017
18th EISCAT symposium Session E6: The ERG mission and magnetosphere-ionosphere coupling May 26 (Fri), NIPR ...
Kasaba, Yasumasa, Ono, Takayuki, Erg Project Team, Takashima, Takeshi, Shiokawa, Kazuo, Higashio, Nana, Seki, Kanako, Kasahara, Satoshi, Kato, Yuto, Oyama, Shin-Ichiro, Matsuoka, Ayako, Asamura, Kazushi, Kazama, Yoich, pulsating aurora team, Miyoshi, Yoshizumi, Wang, Shiang-Yu, Yagitani, Satoshi, Kasahara, Yoshiya, Hosokawa, Keisuke, Shinohara, Iku, Ogawa, Yasunobu, Hikishima, Mitsuru, Mitani, Takefumi, Yokota, Shoichiro, Kojima, Hirotsugu, Kurata, Satoshi   +25 more
core   +1 more source

Unilateral electronegative ERG in a presumed central retinal artery occlusion

, 2010
Luiz H Lima1, Wener Cella2,4, Claudia Brue5, Stephen H Tsang2.31Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil; 2Department of Ophthalmology, 3Bernard and Shirlee Brown Glaucoma Laboratory, Edward S Harkness Eye Institute and Departments of
Claudia Brue, et al, Luiz H Lima, Wener Cella   +3 more
core  

Multifocal ERG in multiple evanescent white dot syndrome

, 2002
PURPOSE: To investigate the electrophysiological findings of a multifocal ERG in multiple evanescent white dot syndrome (MEWDS). METHODS: Multifocal electroretinograms (mf-ERG) were recorded from four patients with MEWDS.
Feigl, Beatrix, Haas, Anton, El-Shabrawi, Yosuf   +2 more
core   +1 more source

Spatial variability of multi-controlled aeolian supersurfaces in central-erg and marine-erg-margin systems [PDF]

, 2013
During the Albian Iberia was under the influence of the Northern-Hemisphere Hot Arid Belt favouring the development of an extensive sandy desert system with a marine-erg margin where prograding aeolian dunes interacted with Tethyan waters.
Sedimentology, Rodríguez-López, J.P., Meléndez, N., Liesa, C.L., de Boer, P.L., Soria, A.R.   +5 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Bipolar Androgen Therapy as a Potential Mechanistic Bridge to Enhance PARP Inhibitor Efficacy in Prostate Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Prostate cancer remains a leading cause of cancer‐related mortality, largely driven by progression to metastatic castration‐resistant prostate cancer (mCRPC). Although poly(ADP‐ribose) polymerase inhibitors (PARPis) have improved outcomes in patients with homologous recombination repair (HRR) alterations, particularly in BRCA2‐mutated disease,
Jhen‐Hao Jhan, Jiun‐Hung Geng, Hung‐Lung Ke, Shu‐Pin Huang, Li Jia   +4 more
wiley   +1 more source

TMPRSS2–ERG-Mediated Feed-Forward Regulation of Wild-Type ERG in Human Prostate Cancers

, 2011
Recurrent gene fusions involving ETS family genes are a distinguishing feature of human prostate cancers, with TMPRSS2–ERG fusions representing the most common subtype.
Scott A. Tomlins, Lei Wang, Matthew K. Iyer, Qi Cao, Sooryanarayana Varambally, Arul M. Chinnaiyan, J. Chad Brenner, Robert J. Lonigro, Xuhong Cao, Ram-Shankar Mani, Aparna Ghosh   +10 more
core   +1 more source

Artificial intelligence, equity, and pediatric neurodevelopmental disorders: A scoping review of clinical practice applications

Pediatric Investigation, EarlyView.
Artificial intelligence (AI) is being explored to support diagnosis and care for pediatric neurodevelopmental disorders, yet most tools remain in early stages of development. This scoping review identifies limited external validation, narrow population representation, and sparse equity considerations, underscoring the need for inclusive, clinically ...
Florida Uzoaru, Obinna O. Oleribe, Ucheoma Nwaozuru, Parichart Sabado   +3 more
wiley   +1 more source