Results 111 to 120 of about 84,102 (243)
Adıyaman Üniversitesi Sağlık Bilimleri DergisiAim: ERG overexpression driven by gene fusions is well-characterized event in prostate cancer, yet its impact on gene expression profiles and regulatory networks remains unclear.
Perçin Pazarcı
doaj +1 more source
, 2015 Presented at the 106th Annual Meeting of the American Urological Association (AUA), May 14-19 2011, Washington, DC, USA BACKGROUND: TMPRSS2-ERG fusions have been identified in about one-half of all prostatic adenocarcinomas (PCa).
Antoun Toubaji (748371) +7 more
core +1 more source
Retinal dystrophies simulating geographic atrophy: A diagnostic challenge
Acta Ophthalmologica, EarlyView.Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn +3 more
wiley +1 more source
Altered differentiation in acute myeloid leukemias; Role of ERG and FUS-ERG fusion protein [PDF]
, 2005 The FUS-ERG chimeric oncogene has been associated with fatal acute myeloid leukemias (AML) carrying the non-random t(16;21) (p11;q22) chromosomal aberration.
Doarn, Michael C.
core +1 more source
Network analysis of master regulators associated with invasive phenotypes in multiple myeloma
Frontiers in Cell and Developmental BiologyTo elucidate the role of transcriptional regulators (TRs) associated with invasiveness in multiple myeloma (MM), we conducted a systematic network analysis to identify key master regulators (MRs) that govern MM invasiveness.
Feng Qian, Yubo Wang, Qinghong Shi
doaj +1 more source
Community Co-Design of a Quick Guide to Inform Digital Health Promotion Strategies for Asymptomatic Women at Risk of Chronic Disease. [PDF]
Health Promot J AustrABSTRACT Introduction Chronic diseases are a leading cause of illness, disability, and death in Australian women. Co‐design research methodologies offer promising approaches to developing community‐centred solutions that improve engagement with preventive health. This community‐driven research explored ways to improve the prevention and early detection
Borquez-Arce P +5 more
europepmc +2 more sources
Clinical and molecular features of PRCD‐associated retinopathy
Acta Ophthalmologica, EarlyView.Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin +30 more
wiley +1 more source
British Journal of Clinical Psychology, EarlyView.Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert +2 more
wiley +1 more source
A novel myopathy with autophagic vacuoles associated with biallelic variants in CLN8
Brain Pathology, EarlyView.We describe a novel adult‐onset myopathy with autophagic vacuoles and characteristic features of ceroid lipofuscinosis associated with biallelic CLN8 variants, seizures, and muscle weakness. Autophagosomal/lysosomal deposition of curvilinear, autofluorescent material containing the mitochondrial adenosine triphosphate (ATP) synthase membrane subunit c ...
Ulrika Lindgren +5 more
wiley +1 more source
Role of the 5′ UTR region in ERG and Tmprss2:ERG variants expression.
, 2013 (A) The native 5′ UTR of ERG-1b, ERG-1c and T1:E4 were replaced with a common one from the expression vector (in orange), and an optimized Kozak sequence.
Francesca Zammarchi (385286) +2 more
core +1 more source