Results 51 to 60 of about 712 (172)
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
British Journal of Pharmacology, Volume 183, Issue 14, Page 3935-3949, July 2026.Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source
Psychedelics, entactogens and psychoplastogens for depression and related disorders
British Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 14, Page 4058-4071, July 2026.Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito +6 more
wiley +1 more source
Ergot alkaloids and summary of biosynthesis pathway.
, 2013 (A) Ergoline alkaloid biosynthesis pathways in the Clavicipitaceae. Arrows indicate one or more steps catalyzed by products of genes indicated. Arrows and genes in blue indicate steps in synthesis of the first fully cyclized intermediate (skeleton ...
Jennifer L. Wiseman (383659) +54 more
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Derivatives as 5HT1A receptor ligands-past and present.
, 2005 A review. Serotonin is a neuromediator, well-know for its implication in mood regulation, anxiety, depression and, insomnia as well as in normal human function such as sleep, sexual activity and appetite. In this way, serotonin (5-hydroxytryptamine, 5-HT)
SANTAGADA, VINCENZO +3 more
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Arylpiperazine derivatives as serotoninergic ligands
, 2009 Serotonin is a neuromediator well known for its implication in mood regulation, anxiety, depression,insomnia as well as in normal human function such as sleep, sexual activity and appetite and recently it was demonstrated its involvement in the ...
SEVERINO B +9 more
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D-1-Carboxymethyl-8β-carboxy-6-methylergoline and some 1,8-disubstituted ergolines derived from it
, 1982 Reaction of D-8β-carboxy-6-methylergoline (I) with ethyl bromo acetate gave D-1-carboxy-8β-carboxy-6-methylergoline (II), whose dimethyl ester III was reduced with sodium borohydride, either selectively to D-1-(2-hydroxyethyl)-8β-methoxycarbonyl-6 ...
Jan Šmidrkal, Miroslav Semonský
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Endophyte in Tall Fescue: Impact on Horses and Cattle [PDF]
, 2011 Tall fescue [Lolium arundinaceum (Schreb.) Darbysh.] is an introduced cool-season perennial grass from Europe. Originally imported for regularly flooded pastures, tall fescue is now widespread across the United States due to its adaptability of a wide ...
Cotton, Krista, Smith, S. Ray
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, 2013 Includes bibliographical references (p. 54-56).I. Diversity-Optimized Route to the Ergoline Skeleton The ergot alkaloids possess perhaps the greatest diversity of any class of natural products.
Burley, Scott D.
core
Towards a biophysical understanding of hallucinogen action
, 2007 The serotonin 2A (5-HT2A) receptor is necessary for the psychopharmacological actions of the serotonergic hallucinogens such as LSD. An exploration of the biophysical actions of hallucinogens at the 5-HT2A receptor may be useful in understanding their ...
Braden, Michael Robert
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