Results 31 to 40 of about 712 (172)

Alkylation of ergoline derivatives at position N(1)

, 1982
N(1)-Alkyl-8β-ergolines I-XII were prepared by alkylation of 8β-ergoline derivatives XIII to XVIII with alkyl halides in dimethyl sulphoxide in the presence of potassium hydroxide. The compounds I-XII exhibited weak inhibition effects on the secretion of
Jan Šmidrkal, Miroslav Semonský
core   +1 more source

Pleuropulmonary changes induced by ergoline drugs [PDF]

European Respiratory Journal, 1996
Classic ergolines, such as bromocriptine, methysergide and ergotamine, can induce chronic pleuropneumonitis. We present the cases of eight patients who developed similar changes whilst on other ergolines. In this retrospective case study spanning 1985-1995, clinical data, radiological material, pulmonary function, bronchoalveolar lavage and ...
P, Pfitzenmeyer, P, Foucher, G, Dennewald, B, Chevalon, D, Debieuvre, P, Bensa, F, Piard, P, Camus   +7 more
openaire   +2 more sources

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

The total syntheses of ring -A substituted ergolines

, 1998
Three types of ergolines, having a substituent in ring A were designed and their total syntheses were attempted. N-substituted 12-methoxyergolines were synthesized as potential serotonergic agents to test the hypothesis of bioisosterism between the C8 ...
Lee, Sunkyung
core   +1 more source

Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts, Youri Bekhuis, Myrthe Stalmans, Wout Lauriks, Martijn Kusters, Karim Taha, Thomas Rosseel, Guido Claessen, Chiel Poffé   +8 more
wiley   +1 more source

Validity and Feasibility of the Constant‐Load Cycle Endurance Test in Lung Cancer Patients Undergoing Radiation Therapy

Thoracic Cancer, Volume 17, Issue 17, September 2026.
The constant‐load cycle endurance test (CET) demonstrated feasibility and validity in lung cancer patients undergoing thoracic radiation therapy. CET may provide complementary information to the 6‐min walk test when evaluating rehabilitation outcomes.
Junghwa Do, Sungeun Park, Sei Won Lee, A. Hyun Kim, Sang Ah Kim, Seung Hak Lee, Hwayeong Cheon, Jae Yong Jeon   +7 more
wiley   +1 more source

Exercise or Fasting in Individuals With Type 2 Diabetes Receiving Once‐Weekly Basal Insulin Icodec

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8523-8532, September 2026.
ABSTRACT Aims To investigate glucose levels and hypoglycaemia risk during exercise or fasting in adults with type 2 diabetes (T2D) treated with once‐weekly basal insulin icodec. Materials and Methods Thirty basal insulin‐treated, physically active individuals with T2D (18–75 years, glycated haemoglobin ≤ 75 mmol/mol, peak oxygen uptake > 20 mL/kg/min ...
Thomas R. Pieber, Harpreet S. Bajaj, Gabriele Fluhr, Klara R. Klein, Thaís M. Pagliaro Rocha, Harald Sourij, Eva Svehlikova, Keerthana Udupa, Sara K. Watt, Maria Willerslev‐Olsen, Rasmus Ribel‐Madsen   +10 more
wiley   +1 more source

Preparation and Use of Nitrogen- or Sulfur Containing Heterocycles in Organic Synthesis

, 1980
The utility of intramolecular cycloadditions of ortho-quinodimethanes for the synthesis of complex polycyclic molecules is illustrated: 1) by the stereoselective synthesis of the natural alkaloid (±)-chelidonine starting from a benzocyclobutene; 2) by ...
Von Oppolzer, Wolfgang
core   +1 more source

Differential effects of central blood volume loading and unloading on pulmonary diffusing capacity in humans

The Journal of Physiology, Volume 604, Issue 18, Page 7957-7970, 15 September 2026.
Abstract figure legend Central blood volume (CBV) is a key haemodynamic determinant of pulmonary diffusing capacity for carbon monoxide (DLCO) and its components, capillary blood volume (Vc) and membrane diffusing capacity (Dm,CO). However the contribution of CBV to DLCO regulation remains poorly defined. We investigated the effects of graded increases
Andrew W. D'Souza, Andrew R. Brotto, Thomas G. Williams, Chuanyi Foo, Eli Bok, Desi P. Fuhr, Jason Weatherald, Sean van Diepen, Michael K. Stickland   +8 more
wiley   +1 more source

Studies on oxidation of ergot alkaloids: oxidation and desaturation of dihydrolysergol-stereochemical requirements

, 2007
A new method for the oxidation of ergoline alcohols to aldehydes was found (TFFA-DMSO, -78 °C, then DIPEA). Structural features of ergolines required for successful C7-C8 double bond introduction via Polonovski-Potier reaction of respective 6-N-oxides ...
P. Sedmera, V. Kren, M. Novotna, D. Passarella, R. Gazak, B. Danieli   +5 more
core   +1 more source