Psychedelic Drugs Rediscovered—In Silico Study of Potential Fetal Exposure to Analogues of Psychedelic Drugs During Pregnancy [PDF]
MoleculesA total of 250 known and novel compounds—ketamine and serotonergic psychedelics or their analogues—designed to target depression, addictions and/or other mental or neurological disorders and developed as “recreational” (illegal) drugs from three chemical
Anna W. Sobańska +2 more
doaj +3 more sources
Biological studies of clavine alkaloids targeting CNS receptors [PDF]
Frontiers in Psychiatry, 2023 In contrast to well established psychedelics such as lysergic acid diethylamide (LSD) and psilocybin, ergot alkaloids of the clavine subclass have not been thoroughly investigated, in spite of their broad occurrence in nature and their well-established ...
Nikhil R. Tasker +2 more
doaj +2 more sources
Psychedelics: A new era of treatment? [PDF]
European Psychiatry, 2021 Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
doaj +2 more sources
High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines. [PDF]
PLoS Genetics, 2016 Invasive infections by fungal pathogens cause more deaths than malaria worldwide. We found the ergoline compound NGx04 in an antifungal screen, with selectivity over mammalian cells.
Ireos Filipuzzi +13 more
doaj +2 more sources
Synthetic Strategies toward Lysergic Acid Diethylamide: Ergoline Synthesis via α-Arylation, Borrowing Hydrogen Alkylation, and C-H Insertion. [PDF]
J Org Chem, 2023 Lysergic acid diethylamide (LSD), a semisynthetic ergoline alkaloid analogue and hallucinogen, is a potent psychoplastogen with promising therapeutic potential.
Tuck JR, Dunlap LE, Olson DE.
europepmc +2 more sources
Galactorrhea: how to address this unusual complication after augmentation mammoplasty [PDF]
Revista Brasileira de Cirurgia Plástica, 2016 INTRODUCTION: Galactorrhea and galactocele formation after breast augmentation are complications reported in the literature, but the cause remains unknown.
Adriana Sayuri Kurogi Ascenço +4 more
doaj +1 more source
Sensors, 2019 Magnetic Induction Tomography (MIT) is a non-invasive imaging technique that has been widely applied for imaging materials with high electrical conductivity contrasts.
Fang Li +3 more
doaj +1 more source
Two new dopamine agonists that are long acting in vivo but short acting in vitro.
, 1980 The effects of two new ergolines, pergolide and CH29-717, on prolactin secretion in vitro and in vivo were compared with those of bromocriptine. Both ergolines had in vitro potencies similar to that of bromocriptine, but had a shorter duration of action.
Grossman, Ashley +5 more
core +2 more sources
Stimulant and hallucinogenic novel psychoactive substances; an update [PDF]
, 2023 Introduction: The renewed interest in considering a range of stimulants, psychedelics and dissociatives as therapeutics emphasizes the need to draft an updated overview of these drugs’ clinical and pharmacological issues.
Amira Guirguis
core +3 more sources
Emerging Trends in Drugs, Addictions, and HealthIntroduction: Serotonergic psychedelics induce their characteristic subjective effects via activation of the serotonin 2A receptor (5-HT2AR). This structurally diverse class of drugs includes ergolines (e.g., LSD), phenethylamines (e.g., mescaline), and ...
E. Pottie +3 more
doaj +1 more source