Results 21 to 30 of about 609 (136)

A 12‐week Exercise Intervention Among Older Adults With Chronic Coronary Syndrome: Changes and Associations of Movement Behaviors and Cardiovascular Risk Factors

European Journal of Sport Science, Volume 26, Issue 7, July 2026.
ABSTRACT Physical activity (PA) is key to improve the prognosis of patients with chronic coronary syndrome (CCS). This study investigated changes in movement behaviors (MB), obesity markers, cardiorespiratory fitness (VO2peak), cardiometabolic risk (CMR), and brain‐derived neurotrophic factor (BDNF) and whether changes in MB are associated with VO2peak,
Antje Ullrich, Martin Bahls, Lisa Voigt, Stephanie Könemann, Marcus Dörr, Susanne Wurm, Sabina Ulbricht   +6 more
wiley   +1 more source

Determinants of Improved Dyspnea and Exercise Tolerance With Nasal High‐Flow O2 Therapy in Fibrotic Interstitial Lung Disease: A Pilot Physiological Study

Respirology, Volume 31, Issue 7, Page 732-744, July 2026.
We tested the respective effect of high‐flow and supplemental O2 from nasal high‐flow O2 therapy (NHFO2) on dyspnea and exercise tolerance in fibrotic interstitial lung disease. Supplemental O2 and NHFO2 (but not high‐flow) provided improvements in these outcomes at “iso‐O2 saturation” due to reduced ventilatory requirements.
Sarah Thivent, Marylise Ginoux, Samuel Verges, Frédéric Hérengt, Mathieu Marillier   +4 more
wiley   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, Volume 183, Issue 14, Page 3970-3991, July 2026.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

British Journal of Pharmacology, Volume 183, Issue 14, Page 3935-3949, July 2026.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, Volume 183, Issue 14, Page 4058-4071, July 2026.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Advancing tele‐physiology: A chest patch solution for continuous, non‐invasive remote monitoring in a hypoxic environment

Experimental Physiology, Volume 111, Issue 7, Page 3280-3293, 1 July 2026.
Abstract Skin‐mounted sensors are thin, flexible and lightweight electronic devices that enable monitoring of multiple physiological parameters. The aim of this study was to provide pilot evidence for possible utilization of a sensorized patch for capturing the bodily response to hypoxia. The subsequent phases of the study comprised a case report and a
Danilo Bondi, Ferdinando Calcagno, Elisa Fioraso, Camillo Di Giulio, Federico Schena, Anna Pedrinolla   +5 more
wiley   +1 more source

Ventilatory efficiency: Physiological modelling and mechanistic validation

The Journal of Physiology, Volume 604, Issue 14, Page 5777-5799, 15 July 2026.
Abstract figure legend From post‐threshold ventilatory linearization to ceiling‐normalized efficiency – conceptual framework underlying ηV̇E$\eta {{\dot{V}}_{\mathrm{E}}}$ Conventional V̇E${{\dot{V}}_{\mathrm{E}}}$–V̇CO2${{\dot{V}}_{{\mathrm{C}}{{{\mathrm{O}}}_2}}}$ slopes are typically derived under submaximal conditions and may become physiologically
Paulo T Muller, Beate Stubbe, Till Ittermann, Erlandson S Ferreira, J A Neder, Ralf Ewert   +5 more
wiley   +1 more source

Physically active adults with uncomplicated type 1 diabetes exhibit normal cardiopulmonary exercise test responses versus healthy controls

Physiological Reports, Volume 14, Issue 13, July 2026.
Physically active adults with uncomplicated type 1 diabetes and healthy controls completed incremental cycling cardiopulmonary exercise testing with measurements at rest, ventilatory thresholds 1 and 2, and peak exercise. Linear mixed‐effects models showed no statistically detectable Group effects or Group × Stage interactions for conventional ...
Samu Sorola, Timo Eronen, Vesa Hyrylä, Saana Kupari, Mika Venojärvi, Heikki Tikkanen, Mika Tarvainen, Harri Lindholm   +7 more
wiley   +1 more source

Oxygen Supplementation Improves Oxygen Uptake Kinetics and Exercise Performance in PAH and CTEPH Patients

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
In patients with pulmonary vascular diseases (PAH and CTEPH), supplemental oxygen (FiO2 0.3), compared to room air (FiO2 0.21) improved peak exercise capacity (peak V̇O2), peak sustainable exercise (V̇O2 at GET), and V̇O2 kinetics and the onset of exercise.
Shir Kadosh, Yael Baidats, Andrew M. Jones, Daryl Wilkerson, Ariela Velner, Ronen Reuveny, Michael J. Segel   +6 more
wiley   +1 more source