Results 21 to 30 of about 1,990 (193)
Ropinirole, a Non‐Ergoline Dopamine Agonist [PDF]
ABSTRACTDopamine agonists have become indispensable in the treatment of Parkinson's disease. In every‐day practice, however, the decision to select the best compound for an individual patient is rendered difficult because of the large number of substances available on the market.
Wolfgang H, Jost, Dieter, Angersbach
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Alkylation of ergoline derivatives at position N(1)
N(1)-Alkyl-8β-ergolines I-XII were prepared by alkylation of 8β-ergoline derivatives XIII to XVIII with alkyl halides in dimethyl sulphoxide in the presence of potassium hydroxide. The compounds I-XII exhibited weak inhibition effects on the secretion of
Jan Šmidrkal, Miroslav Semonský
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Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
wiley +1 more source
Preparation and Use of Nitrogen- or Sulfur Containing Heterocycles in Organic Synthesis
The utility of intramolecular cycloadditions of ortho-quinodimethanes for the synthesis of complex polycyclic molecules is illustrated: 1) by the stereoselective synthesis of the natural alkaloid (±)-chelidonine starting from a benzocyclobutene; 2) by ...
Von Oppolzer, Wolfgang
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dissertationEarlier studies have demonstrated the peroxidase oxidation of the delta8-ergolines agroclavine and elymoclavine to their respective 10-hydroxy-delta9, and other derivatives.
Choong, Tung-Chung.
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Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts +8 more
wiley +1 more source
Pleuropulmonary changes induced by ergoline drugs [PDF]
Classic ergolines, such as bromocriptine, methysergide and ergotamine, can induce chronic pleuropneumonitis. We present the cases of eight patients who developed similar changes whilst on other ergolines. In this retrospective case study spanning 1985-1995, clinical data, radiological material, pulmonary function, bronchoalveolar lavage and ...
P, Pfitzenmeyer +7 more
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Isolation and determination of three new and eight known compounds from the aerial parts of Argyreia mekongensis with their cytotoxic activity against HepG2, MCF‐7, and SK‐LU‐1 cell lines. ABSTRACT Three previously undescribed 21α‐hydroxyoleanolic acid glycosides, designated Argymekosides A–C (1–3), together with eight known compounds (4–11), were ...
Tran Thi Ngoc Hanh +8 more
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A new method for the oxidation of ergoline alcohols to aldehydes was found (TFFA-DMSO, -78 °C, then DIPEA). Structural features of ergolines required for successful C7-C8 double bond introduction via Polonovski-Potier reaction of respective 6-N-oxides ...
P. Sedmera +5 more
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The total syntheses of ring -A substituted ergolines
Three types of ergolines, having a substituent in ring A were designed and their total syntheses were attempted. N-substituted 12-methoxyergolines were synthesized as potential serotonergic agents to test the hypothesis of bioisosterism between the C8 ...
Lee, Sunkyung
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