Results 31 to 40 of about 48,364 (235)

Δ8(9),22-Ergostadiene-3β-ol, an ergosterol precursor accumulated in wild-type and mutants of yeast

Journal of Lipid Research, 1972
Whereas wild-type strains of Saccharomyces cerevisiae can synthesize up to 7% dry weight of ergosterol, a polyene-resistant mutant has been obtained which produces no ergosterol. Instead, a C-28 methyl sterol is produced, and it has been identified as Δ8(
L.W. Parks, F.T. Bond, E.D. Thompson, P.R. Starr   +3 more
doaj   +1 more source

Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study [PDF]

, 2013
Peer reviewedPublisher ...
Gow, Neil A R, Lee, Keunsook, Munro, Carol A, Pietro, Rosemeire C L R, Preechasuth, Kanya, Santos, Emerson, Severi, Juliana A, Souza-Moreira, Tatiana M, Vilegas, Wagner   +8 more
core   +4 more sources

Antioxidant Potential of Ergosterol–Phospholipid Liposomes with Thymus serpyllum Extract

Proceedings
The antioxidant activity of ergosterol–phospholipid liposomes with chemically characterized, encapsulated wild thyme (Thymus serpyllum) extract was examined. 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)
Dragana Dekanski, Andrea Pirković, Diana Lupulović, Predrag Petrović, Aleksandra A. Jovanović   +4 more
doaj   +1 more source

PH regulation of amphotericin B channels activity in the bilayer lipid membrane [PDF]

, 2016
Background: Amphotericin B (AmB) is a polyene antibiotic frequently applied in the treatment of systemic fungal infections in spite of its secondary effects.
Ashrafpour, M., Sepehry, H., Shahmoradi, T.   +2 more
core   +2 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Co-culture with Lactobacillus plantarum SC-1 facilitates ergosterol synthesis in Monascus purpureus through MpSet1-affected H3K4ac establishment

Frontiers in Microbiology
IntroductionIn fungi, ergosterol synthesis is regulated by multiple transcription factors such as Upc2, but the regulation of ergosterol synthesis in Monascus remains unclear.MethodsWe performed a co-culture system of Monascus purpureus (M.
Zhongling Wu, Zhenmin Liu
doaj   +1 more source

Synthesis and Cytotoxic Activity of Novel Ergosterol Peroxide Derivatives with Acrylate or Propionate Side Chain

Natural Product Communications, 2022
A series of novel ergosterol peroxide derivatives with acrylate or propionate side chain were synthesized. All compounds 3a-n were evaluated for their cytotoxicity against four kinds of human carcinoma cell lines (HepG2, MCF-7, HCT-116, and A549).
Ming Bu, Zhiguo Zhang, Gang Li, Chunhua Xie, Xiaohui Du, Guofang Ma, Hongling Li   +6 more
doaj   +1 more source

Comparison of two extraction methods for ergosterol determination in vegetal feeds [PDF]

, 2007
Ergosterol is the principal sterol of fungi in which it plays an essential role in cell membrane and other cellular constituents. This sterol is considered as a good marker of fungal contamination and of mycotoxin production.
Bailly, Jean Denis, Benard, Geneviève, Guerre, Philippe, Tardieu, Didier   +3 more
core  

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Ergosterol Supplementation Improves Furfural Tolerance of Saccharomyces cerevisiae to Produce Ethanol and Its Underlying Mechanism

BioResources, 2022
Furfural produced during lignocellulose pretreatment to reduce the recalcitrance inhibits the growth of Saccharomyces cerevisiae and reduces ethanol yield. To reduce the adverse effect of furfural on S.
Youpiao Jia, Qingyan Zhang, Jun Dai, Xueyun Zheng, Xianzhi Meng, Ranran Zhou, Haitao Yang, Lan Yao, Xiong Chen   +8 more
doaj   +2 more sources