Results 41 to 50 of about 48,364 (235)
Frontiers in Cellular and Infection Microbiology, 2017 Candida albicans is one of the most common fungal pathogens. Our previous study demonstrated that concomitant use of berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant C.
Yi Xu +8 more
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Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs. [PDF]
PLoS Pathogens, 2010 Ergosterol is an important constituent of fungal membranes. Azoles inhibit ergosterol biosynthesis, although the cellular basis for their antifungal activity is not understood.
Yong-Qiang Zhang +5 more
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Antioxidant Properties of Ergosterol and Its Role in Yeast Resistance to Oxidation
Antioxidants, 2021 Although the functions and structural roles of sterols have been the subject of numerous studies, the reasons for the diversity of sterols in the different eukaryotic kingdoms remain unclear.
Sebastien Dupont +11 more
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The Multifunctional Fungal Ergosterol [PDF]
mBio, 2018 The roles of ergosterol in the regulation of membrane fluidity and structure, as well its role as a target for the activity of antifungals, have been known for decades. Two recent studies, however, demonstrated that ergosterol is an immunologically active lipid that induces pyroptosis and that virtually all steps of its biosynthetic process are ...
openaire +3 more sources
Quantifying carbon allocation to mycorrhizal fungi by temperate forest tree species across a nitrogen availability gradient [PDF]
, 2013 Terrestrial ecosystems make up the largest carbon pool with a major portion of that being forests. With carbon being a major concern due to global climate change, being able to make accurate models is increasingly important. Studies have shown that trees
Tumber-Davila, Shersingh Joseph
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Animal Research and One Health, EarlyView.This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen +2 more
wiley +1 more source
Research Progress on Ergosterol in Edible Fungi
Liang you shipin ke-jiErgosterol is a sterol compound widely found in edible fungi and has become a research hotspot in functional components in recent years due to its various physiological activities such as anti-inflammation, immune regulation, uric acid reduction, and ...
ZHANG Xin-wei +4 more
doaj +1 more source
mBio, 2018 Phagocytic cells such as macrophages play an important role in the host defense mechanisms mounted in response to the common human fungal pathogen Candida albicans. In vitro, C.
Kristy Koselny +5 more
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Asymmetric Reduction of Unactivated Alkenes
Chemistry – A European Journal, EarlyView.Unactivated alkenes rank among the most inert functional groups in synthesis and their selective reduction remains challenging. This Review charts the evolution from classical metal‐catalyzed hydrogenation to radical hydrogen atom transfer (HAT) and emerging biocatalytic concepts, highlighting how complementary mechanistic strategies, including the ...
Nico D. Fessner +3 more
wiley +1 more source
Microbiological components in mainstream and sidestream cigarette smoke
Tobacco Induced Diseases, 2012 Background Research has shown that tobacco smoke contains substances of microbiological origin such as ergosterol (a fungal membrane lipid) and lipopolysaccharide (LPS) (in the outer membrane of Gram-negative bacteria).
Lennart Larsson +3 more
doaj +1 more source