Results 41 to 50 of about 31,220 (236)

Ergosterol Supplementation Improves Furfural Tolerance of Saccharomyces cerevisiae to Produce Ethanol and Its Underlying Mechanism

BioResources, 2022
Furfural produced during lignocellulose pretreatment to reduce the recalcitrance inhibits the growth of Saccharomyces cerevisiae and reduces ethanol yield. To reduce the adverse effect of furfural on S.
Youpiao Jia, Qingyan Zhang, Jun Dai, Xueyun Zheng, Xianzhi Meng, Ranran Zhou, Haitao Yang, Lan Yao, Xiong Chen   +8 more
doaj   +2 more sources

Requirement for Ergosterol in Berberine Tolerance Underlies Synergism of Fluconazole and Berberine against Fluconazole-Resistant Candida albicans Isolates

Frontiers in Cellular and Infection Microbiology, 2017
Candida albicans is one of the most common fungal pathogens. Our previous study demonstrated that concomitant use of berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant C.
Yi Xu, Hua Quan, Hua Quan, Yan Wang, Hua Zhong, Jun Sun, Jianjiang Xu, Nuan Jia, Yuanying Jiang   +8 more
doaj   +1 more source

Aspergillus oryzae accelerates the conversion of ergosterol to ergosterol peroxide by efficiently utilizing cholesterol

Frontiers in Genetics, 2022
It is well-known that excessive cholesterol leads to hypercholesterolemia, arteriosclerosis, coronary heart disease, stroke, and other diseases, which seriously threatens human health. Lactobacillus, a prokaryote, is reported to utilize cholesterol in the environment. However, little research focuses on the cholesterol utilization by eukaryote.
Shangkun Qiu, Qicong Liu, Ya Yuan, Hong Zhou, Bin Zeng   +4 more
openaire   +3 more sources

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Effects of Wavelength of Ultraviolet Ray on the Formation Rate of Pre-vitamin D_2 From Ergosterol [PDF]

, 1996
P(論文)In the ultraviolet (hereafter called UV) irradiation of ergosterol, the effects of wavelength (UV irradiation lamp 254nm and 310nm) were investigated on the formation of pre-vitamin D_2.
タカムラ, カズノリ, ナカザワ, タケシ, 11504, 11503, 11506, 11505, 11508, HOSHINO, HIROKO, 11507, トヨマス, テツオ, 豊増, 哲郎, 11500, 11502, 11501, 田中, 徳夫, ホシノ, ヒロコ, 11494, タナカ, ノリオ, TOYOMASU, TETSUO, TANAKA, NORIO, NAKAZAWA, TAKESHI, 星野, 浩子, TAKAMURA, KAZUNORI, 11496, 11495, 11498, 11497, 中沢, 武, 高村, 一知, 11499   +29 more
core  

Investigations of Chlamydomonas reinhardtii ergosterol biosynthesis [PDF]

, 2009
Ergosterol is the major sterol found in the membranes of Chlamydomonas reinhardtii. While past studies have identified some ergosterol mutants in C. reinhardtii, very little is known about sterol biosynthesis pathways in this species.
Brumfield, Kristy Marie
core   +1 more source

A Genome-Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis

mBio, 2018
Phagocytic cells such as macrophages play an important role in the host defense mechanisms mounted in response to the common human fungal pathogen Candida albicans. In vitro, C.
Kristy Koselny, Nebibe Mutlu, Annabel Y. Minard, Anuj Kumar, Damian J. Krysan, Melanie Wellington   +5 more
doaj   +1 more source

Impaired biosynthesis of ergosterol confers resistance to complex sphingolipid biosynthesis inhibitor aureobasidin A in a PDR16-dependent manner

Scientific Reports, 2023
Complex sphingolipids and sterols are coordinately involved in various cellular functions, e.g. the formation of lipid microdomains. Here we found that budding yeast exhibits resistance to an antifungal drug, aureobasidin A (AbA), an inhibitor of Aur1 ...
Shizuka Fukuda, Yushi Kono, Yohei Ishibashi, Mitsuaki Tabuchi, Motohiro Tani   +4 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Limosilactobacillus fermentum Limits Candida glabrata Growth by Ergosterol Depletion

, 2023
Candida glabrata is a human-associated opportunistic fungal pathogen. It shares its niche with Lactobacillus spp. in the gastrointestinal and vaginal tract. In fact, Lactobacillus species are thought to competitively prevent Candida overgrowth.
Gattesco, Arianna (University of Natural Resources and Life Sciences, Vienna), Pap, Ildiko-Julia (University Hospital of St. Pölten), Beyer, Reinhard (University of Natural Resources and Life Sciences, Vienna), Zangl, Isabella (University of Natural Resources and Life Sciences, Vienna), Schüller, Christoph (Institute of Microbial Genetics / University of Natural Resources and Life Sciences, Vienna), Labuda, Roman (University of Veterinary Medicine, Vienna / University of Natural Resources and Life Sciences, Vienna), Strauss, Joseph (Institute of Microbial Genetics / University of Natural Resources and Life Sciences, Vienna)   +6 more
core   +1 more source