Results 61 to 70 of about 8,478 (179)

A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity. [PDF]

PLoS ONE, 2014
Functional selectivity is a property of G protein-coupled receptors that allows them to preferentially couple to particular signaling partners upon binding of biased agonists.
Maria Martí-Solano, Ferran Sanz, Manuel Pastor, Jana Selent   +3 more
doaj   +1 more source

Report from the 5th international symposium on mycotoxins and toxigenic moulds : challenges and perspectives (MYTOX) held in Ghent, Belgium, May 2016 [PDF]

, 2016
The association research platform MYTOX “Mycotoxins and Toxigenic Moulds” held the 5th meeting of its International Symposium in Ghent, Belgium on 11 May 2016.[...
Audenaert, Kris, Croubels, Siska, De Saeger, Sarah   +2 more
core   +2 more sources

A Review of Infectious and Non‐Infectious Causes of Pregnancy Loss in Goats

Reproduction in Domestic Animals, Volume 61, Issue 3, March 2026.
ABSTRACT Goats play a vital role in global agriculture, particularly in developing regions, and are increasingly kept as companion animals. Given their economic and social importance, pregnancy losses in goats represent a substantial challenge, leading to considerable economic losses and raising concerns about animal welfare and public health, as some ...
Friederike Maria Kaus, Hannah Eggimann, Barbara Tschulena, Gaby Hirsbrunner, Patrik Zanolari   +4 more
wiley   +1 more source

Effects of hallucinogenic drugs on the human heart

Frontiers in Pharmacology
Hallucinogenic drugs are used because they have effects on the central nervous system. Their hallucinogenic effects probably occur via stimulation of serotonin receptors, namely, 5-HT2A-serotonin receptors in the brain.
Joachim Neumann, Stefan Dhein, Uwe Kirchhefer, Britt Hofmann, Ulrich Gergs   +4 more
doaj   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Stroke‐Like Migraine Attacks After Radiation Therapy (SMART) Syndrome: A Case Report and Review of a Rare Delayed Complication of Cranial Irradiation

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT SMART syndrome is a rare, delayed complication of cranial irradiation that can mimic stroke, tumor recurrence, or autoimmune encephalitis. Early recognition based on clinical‐radiologic features is critical to avoid misdiagnosis and unnecessary interventions since conservative management often leads to complete recovery.
Shiv Jha, Yugant Khand, Surabhi Ranjan, Monika Pandit, Eric Mariuma   +4 more
wiley   +1 more source

A Review of Nanoparticle‐Based Astrocyte Modulation in CNS Disorders: Evaluating the Underexplored Potential of Intranasal Delivery

Nano Select, Volume 7, Issue 1, January 2026.
Nanoparticle‐driven nose‐to‐brain drug delivery offers a noninvasive approach to bypass the blood–brain barrier (BBB) and directly modulate reactive astrocytes in CNS disorders. This review highlights biodegradable nanoparticles for astrocyte modulation, enhancing drug bioavailability, sustained release, and neuroinflammation control.
Senamile M. Dlamini, Gillian D. Mahumane, Pradeep Kumar, Yahya E. Choonara   +3 more
wiley   +1 more source

Upper limb artery segmental occlusions due to chronic use of ergotamine combined with itraconazole, treated by thrombolysis

Thrombosis Journal, 2011
Background The ergotamine tartrate associated with certain categories of drugs can lead to critical ischemia of the extremities. Discontinuation of taking ergotamine is usually sufficient for the total regression of ischemia, but in some cases it could ...
Nodari Franco, Maffeis Roberto, Gheza Federico, Battaglia Giuseppe, Bonardelli Stefano, Cervi Edoardo, Maroldi Roberto, Giulini Stefano M   +7 more
doaj   +1 more source

Scientific Opinion on Ergot alkaloids in food and feed [PDF]

EFSA Journal, 2012
<p>The European Food Safety Authority (EFSA) was asked by the European Commission to deliver a scientific opinion on ergot alkaloids (EAs) in food and feed. EAs are produced by several members within the fungal orders of Hypocreales and Eurotiales.
EFSA Panel on Contaminants in the Food Chain
doaj   +1 more source

An integrated targeted and untargeted approach for the analysis of ergot alkaloids in cereals using UHPLC - hybrid quadrupole time-of-flight mass spectrometry [PDF]

, 2015
An ultra-high performance liquid chromatography hybrid quadrupole time of flight (Q-TOF) mass spectrometry (MS) method is described for the simultaneous quantitative determination of common ergot alkaloids and the screening, detection and identification ...
Arroyo Manzanares, Natalia, De Saeger, Sarah, Diana Di Mavungu, José, García-Campaña, Ana M, Gámiz-Gracia, Laura, Uka, Valdet   +5 more
core   +2 more sources