Results 81 to 90 of about 13,168 (257)

Updated Evaluation of IV Dihydroergotamine (DHE) for Refractory Migraine: Patient Selection and Special Considerations

open access: yesJournal of Pain Research, 2020
Rafia Shafqat, Yadira Flores-Montanez, Victoria Delbono, Stephanie J Nahas Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USACorrespondence: Stephanie J Nahas 900 Walnut St., Suite 200, Philadelphia, PA 19107-5509, USATel +1 215 ...
Shafqat R   +3 more
doaj  

O padrão biológico da cefaléia cervicogênica pode ser alterado pelo uso excessivo de ergotamínicos ou pela sua retirada? Can the biologic pattern of cervicogenic headache change after overuse or withdrawal of the ergotamine derivatives?

open access: yesArquivos de Neuro-Psiquiatria, 2000
A transformação de uma cefaléia primária em cefaléia crônica diária (CCD) pode ou não estar relacionada com o abuso de analgésicos, pois a influência desse abuso sobre os mecanismos fisiopatológicos permanecem inconclusivos.
ELCIO JULIATO PIOVESAN   +4 more
doaj   +1 more source

Computational View toward the Inhibition of SARS-CoV-2 Spike Glycoprotein and the 3CL Protease

open access: yesComputation, 2020
Since the outbreak of the 2019 novel coronavirus disease (COVID-19), the medical research community is vigorously seeking a treatment to control the infection and save the lives of severely infected patients. The main potential candidates for the control
Zhen Qiao   +3 more
doaj   +1 more source

Potential of solid state fermentation for production of ergot alkaloids [PDF]

open access: yes, 1992
Production of total ergot alkaloids by #Claviceps fusiformis$ in solid state fermentation was 3.9 times higher compared to that in submerged fermentation.
Lonsane, B.K.   +3 more
core   +1 more source

An integrated targeted and untargeted approach for the analysis of ergot alkaloids in cereals using UHPLC - hybrid quadrupole time-of-flight mass spectrometry [PDF]

open access: yes, 2015
An ultra-high performance liquid chromatography hybrid quadrupole time of flight (Q-TOF) mass spectrometry (MS) method is described for the simultaneous quantitative determination of common ergot alkaloids and the screening, detection and identification ...
Arroyo Manzanares, Natalia   +5 more
core   +2 more sources

Novel 4,5‐Dihydrothiazole‐Phenylpiperazine Derivatives: Synthesis, Docking Studies and Pharmacological Evaluation as Serotonergic Agents

open access: yesChemMedChem, Volume 20, Issue 15, August 2, 2025.
The synthesis of a new series of 4,5‐dihydrothiazol‐2‐ylphenylpiperazine derivatives as serotoninergic ligands is described and tested for their affinity toward 5‐HT1A, 5‐HT2A,and 5‐HT2C and selected for further in vivo assays to determine their functional activity. The pharmacological studies highlight that among the developed derivatives, FG‐7 and FG‐
Giorgia Andreozzi   +18 more
wiley   +1 more source

Assessing Self‐medication Practices Among Healthcare Providers With Migraine in Saudi Arabia

open access: yesBrain and Behavior, Volume 15, Issue 8, August 2025.
ABSTRACT Objectives Migraine is a neurological disorder characterized by recurrent headaches resulting from abnormal regulation of sensory input to the head. Self‐medication (SM) is a prevalent practice among healthcare providers (HCPs), with potentially detrimental consequences.
Bandar Nasser Aljafen   +6 more
wiley   +1 more source

Prevalence, characteristics and management of headache experienced by people with schizophrenia and schizoaffective disorder: a cross sectional cohort study [PDF]

open access: yes, 2017
Objective: Headache is the most common type of pain reported by people with schizophrenia. This study aimed to establish prevalence, characteristics and management of these headache.
Connaughton, J, Wand, B
core   +2 more sources

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

open access: yesAdvanced Theory and Simulations, Volume 8, Issue 7, July 2025.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak   +2 more
wiley   +1 more source

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