Results 151 to 160 of about 5,857,373 (241)

Herpesvirus genome integration in whole‐genome sequences of dementia and control cohorts

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The infectious hypothesis suggests that microbes like herpesviruses may play a role in the pathogenesis of Alzheimer's disease (AD) and other related dementias through methods that may include viral genome integration. The occurrence of herpesvirus genome integration in dementia patients has not been thoroughly characterized ...
Stacey L. Piotrowski   +27 more
wiley   +1 more source

Molecular Characterization Of Vibrio Species Isolated From Seawater [PDF]

open access: yes, 2001
A study was conducted to determine the prevalence of Vibrio species in seawater samples obtained from the coast of Malacca, Penang (Batu Feringgi , George Town), and Terengganu, respectively. Four Vibrio cholerae 0139, 10 V.
Yuherman,
core  

Population pharmacokinetics and exposure–response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 980-996, March 2026.
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao   +12 more
wiley   +1 more source

Clinical, biological and cytometric characteristics of two patients with a homozygous A91V PRF1 mutation

open access: yesClinical &Translational Immunology, Volume 15, Issue 3, 2026.
Familial haemophagocytic lymphohistiocytosis (FHL) is a rare, inherited granzyme–perforin system defect that predisposes individuals to haemophagocytic lymphohistiocytosis. This article presents two original case reports of FHL type 2, along with a comprehensive literature review. Together, these elements aim to enhance the current understanding of FHL
Nicolas Perrard   +12 more
wiley   +1 more source

Incidence and Molecular Typing of Vibrio parahaemolyticus from Tiger Shrimp Culture Environments along the Southwest Coast of India [PDF]

open access: yes, 2009
Vibrio parahaemolyticus is one of the most prevalent food-borne pathogens along the southwest coast of India, where marine foods are frequently consumed.
Chakraborty, Rekha D, Surendran, P K
core  

Small dietary changes yield growth benefits in lesser black‐backed gull chicks

open access: yesJournal of Avian Biology, Volume 2026, Issue 2, March 2026.
Global environmental changes alter the availability and predictability of marine resources, forcing marine predators to adapt their diets and foraging strategies. Lesser black‐backed gulls Larus fuscus exhibit individual differences in foraging consistency within and across years, which could influence reproductive success.
Mélibée Morel   +6 more
wiley   +1 more source

Identification of Sinorhizobium (Ensifer) medicae based on a specific genomic sequence unveiled by M13-PCR fingerprinting [PDF]

open access: yes, 2009
A collection of nodule isolates from Medicago polymorpha obtained from southern and central Portugal was evaluated by M13-PCR fingerprinting and hierarchical cluster analysis.
Ana Catarina Dourado   +6 more
core   +3 more sources

SIRT7 Orchestrates Ligand‐Dependent ERα Signaling Rewiring to Drive Tamoxifen Resistance in ERα‐positive Breast Cancer

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
In tamoxifen‐sensitive breast cancer, SIRT7 deacetylates ERα at lysines 302 and 303, promoting CHIP‐mediated, ubiquitin‐dependent proteasomal degradation of ERα and thereby restraining estrogen‐driven tumor growth. By contrast, during tamoxifen treatment, enhanced interaction between SIRT7 and ERα redirects deacetylated ERα toward activation of EGFR ...
Yalan Wu   +14 more
wiley   +1 more source

Molecular Profiling and Antibiotic Resistance of Salmonella Enterica Subsp. Enterica Isolated from Indigenous Ulam and Poultry Meat [PDF]

open access: yes, 2007
Salmonella enterica subsp. enterica formed the major group that represents nearly 60% of the salmonellae. Salmonella organisms emerged as a public health problem in many countries as salmonellosis has become the most prevalent foodborne disease ...
Lee, Learn Han
core  

Distinct contributions of O‐acetylserine sulfhydrylases to cysteine biosynthesis in Pseudomonas aeruginosa

open access: yesProtein Science, Volume 35, Issue 3, March 2026.
Abstract Cysteine biosynthesis in bacteria proceeds primarily via the de novo pathway, involving serine acetyltransferase (CysE) and O‐acetylserine sulfhydrylase (OASS). This pathway is absent in humans, and its inhibition impairs microbial fitness, virulence, and antibiotic resistance, making its enzymes attractive antimicrobial targets. Most bacteria
Noemi Massa   +10 more
wiley   +1 more source

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