Liraglutide inhibits the proliferation of rat hepatic stellate cells under high glucose conditions by suppressing the ERK signaling pathway. [PDF]
Fan B +7 more
europepmc +1 more source
Retraction Note: Reducing PKCδ inhibits tumor growth through growth hormone by inhibiting PKA/CREB/ERK signaling pathway in pituitary adenoma. [PDF]
Chen X +10 more
europepmc +1 more source
Imiquimod, a Promising Broad-Spectrum Antiviral, Prevents SARS-CoV-2 and Canine Coronavirus Multiplication Through the MAPK/ERK Signaling Pathway. [PDF]
Vicente J +7 more
europepmc +1 more source
JSAP1 Suppresses the ERK MAPR Signaling Pathways
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Nodakenin Inhibits Melanogenesis Via the ERK/MSK1 Signaling Pathway.
Die Pharmazie, 2023The aim of the present study was to investigate the potential inhibitory effects of nodakenin, a coumarin glucoside derivative from the root extract of Angelica gigas Nakai (AGN), on melanogenesis and its underlying mechanisms in B16F10 melanoma cells.
Yeahwa Yoon, Yeahwa Yoon +4 more
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GNA13 inhibits glioblastoma metastasis via the ERKs/FOXO3 signaling pathway
Cellular Signalling, 2023Glioblastoma (GBM) is a malignant tumor characterized by poor prognosis and low overall survival (OS) rate. Identification of novel biological markers for the diagnosis and treatment of GBM is crucial to developing interventions to improve patient survival.
Qingfeng, Yi +8 more
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Annexin1 regulates the erythroid differentiation through ERK signaling pathway
Biochemical and Biophysical Research Communications, 2005K562 cells can be used as a model of erythroid differentiation on being induced by hemin. We found that the level of annexin1 gene expression was notably increased during this indicated process. To test the hypothesis that annexin1 can regulate erythropoiesis, K562 cell clones in which annexin1 was stably increased and was knocked down by RNAi were ...
Xiao-fang, Huo, Jun-Wu, Zhang
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Sorafenib regulating ERK signals pathway in gastric cancer cell
Environmental Toxicology and Pharmacology, 2014The involvement of ERK signals in gastric carcinoma was investigated using Western blot, MTT, and flow cytometric analysis in cultured cells SGC7901. Results showed that treatment of sorafenib potently inhibited gastric SGC7901 cells proliferation, migration, invasion as well as promoted apoptosis.
Liu Wei, Juan +4 more
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PARP-1 activation in the ERK signaling pathway
Trends in Pharmacological Sciences, 2007PARP-1 is a highly conserved DNA-binding protein, the most abundant member of the polyADP-ribose polymerases (PARP) family, which catalyzes post-translational modification of proteins by polyADP-ribosylation. This modification affects protein-protein and protein-DNA interactions.
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