Results 1 to 10 of about 331,296 (302)
The effect of high-intensity interval swimming training on CREB and ERK proteins of hippocampus tissue in elderly rats [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2023 Background and Purpose: Cognitive impairment caused by aging has become one of the most common health threats in many countries. Signaling pathways are important moderators of various physiological and pathological processes, and abnormal activation of ...
Zahra Sabri, Mozhgan Ahmadi
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Anti-tumor mechanism of evodiamine on gastric cancer cells in vitro through MAPK signaling pathway
Di-san junyi daxue xuebao, 2021 Objective To investigate the anti-tumor effect of evodiamine on gastric cancer cells via the MAPK signaling pathway. Methods MTT assay was used to assess the cell viability of SGC-7901 cells after the treatment of 8, 16 and 32 μmol/L evocarpine (denoted ...
QIAN Weina +4 more
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Di-san junyi daxue xuebao, 2021 Objective To investigate the effects of oncostatin M (OSM) on the proliferation and extracellular matrix secretion of human dermal fibroblasts (HDFs) in high glucose environment and its possible mechanism.
LIU Lulu, FU Xueming, XUE Biyu, XUE Bin
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Autoimmunity, 2022 Rheumatoid arthritis is troublesome to treat effectively and often requires concomitant long-term treatment. Meanwhile, synovial fibroblasts could induce inflammation response and lead to joint erosion, finally causing progressive joint destruction ...
Jun Liu +7 more
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Di-san junyi daxue xuebao, 2021 Objective To investigate the anti-tumor effect of sorafenib (Sor) combined with Ophiopogonin D'(OPD') on androgen-independent prostate cancer (PC3) cells and its mechanism.
ZHANG Yaowen +3 more
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Frontiers in Bioscience-Landmark, 2023 Background: The mortality rate of colorectal cancer (CRC) ranks second worldwide. Previous research had indicated that licochalcone A (LA) was a flavonoid in licorice with diverse anticancer effects.
Tianpeng Li +11 more
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Identification of sphingosine 1-phosphate level and MAPK/ERK signaling in pancreatic β cells [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2021 Purpose Sphingosine kinase is a lipid kinase that phosphorylates sphingosine to generate sphingosine 1-phosphate (S1P). S1P regulates pancreatic islet β-cell endoplasmic reticulum stress and proliferation.
Ji Hyun Park +3 more
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Animal Cells and Systems, 2020 Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this ...
Zobia Umair +9 more
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Zhongliu Fangzhi Yanjiu, 2020 Objective To investigate the expression and significance of GPNMB, ERK, MMP3 and MMP9 in primary lesion and bone metastasis of renal cell carcinoma, and to analyze their correlation.
ZHAI Jianpo +4 more
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Radiology and Oncology, 2019 Endometrial adenocarcinoma (EAC) is one of the most commonly diagnosed gynaecological malignancies among female population of the developed countries. DUSP6 is a negative regulator of ERK signaling, which is a molecular switch involved in MAPK signaling ...
Fan Ming-Jun +5 more
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