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p38 MAPK signalling in osteoblast differentiation [PDF]
Frontiers in Cell and Developmental Biology, 2016 The skeleton is a highly dynamic tissue whose structure relies on the balance between bone deposition and resorption. This equilibrium, which depends on osteoblast and osteoclast functions, is controlled by multiple factors that can be modulated post ...
Edgardo eRodríguez-Carballo +2 more
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International Journal of Molecular Sciences, 2021 p38 Mitogen activated protein kinases (p38MAPK) are a highly evolutionary conserved group of protein kinases, which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration, and tumour formation [...]
Juan José Sanz-Ezquerro, Ana Cuenda
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Folia Histochemica et Cytobiologica, 2022 INTRODUCTION: Suppressing the phenotype of cancer stem cells (CSCs) is a promising treatment strategy for cancer. P38 mitogen-activated protein kinases (MAPK, p38) play an important role in the occurrence, development, and stemness maintenance of tumors.
Jin Zhao +5 more
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Effect and mechanism of H. pylori in regulation of REDD1 expression in gastric mucosa
Di-san junyi daxue xuebao, 2022 Objective Regulated in development and DNA damage responses-1 (REDD1) is a conserved and ubiquitous protein, and is induced in response to multiple stimuli. However, its regulation, function and clinical relevance in Helicobacter pylori (H.
YAN Zongbao +4 more
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The Effect of Doxycycline on PMA-Induced MUC5B Expression via MMP-9 and p38 in NCI-H292 Cells [PDF]
Clinical and Experimental Otorhinolaryngology, 2011 ObjectivesDoxycycline is commonly used in medicine for its bacteriostatic antimicrobial properties. Recent studies have reported that doxycycline also has anti-inflammatory effects.
Chang Hoon Bae +4 more
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Nutrition & Metabolism, 2021 Background Androgen receptor (AR) exerts important roles in exercise-induced alterations of muscle mass, in which the proliferation and differentiation of satellite cells or myoblasts are crucial.
Shaoting Fu +3 more
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Frontiers in Cell and Developmental Biology, 2022 Cardiac reactive fibrosis is a fibroblast-derived maladaptive process to tissue injury that exacerbates an uncontrolled deposition of large amounts of extracellular matrix (ECM) around cardiomyocytes and vascular cells, being recognized as a pathological
Yu Tian +9 more
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Frontiers in Pharmacology, 2021 Myocardial fibrosis is closely related to high morbidity and mortality. In Inner Mongolia, Gentianella amarella subsp. acuta (Michx.) J.M.Gillett (G. acuta) is a kind of tea used to prevent cardiovascular diseases.
Hong-Xia Yang +17 more
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Particle and Fibre Toxicology, 2023 Background Polypropylene (PP) is used in various products such as disposable containers, spoons, and automobile parts. The disposable masks used for COVID-19 prevention mainly comprise PP, and the disposal of such masks is concerning because of the ...
Jong-Hwan Woo +6 more
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ERK, p38 AND NF-kappaB SIGNALING IN MONOCYTE DERIVED DENDRITIC CELLS IN PATIENTS WITH MYELODYSPLASTIC SYNDROME. [PDF]
Journal of IMAB, 2014 We have previously demonstrated that in patients with myelodysplastic syndrome (MDS) monocyte-derived DCs (MoDC) exhibit some phenotypic and functional abnormalities. However, the mechanisms underlying the defective response have not yet been clarified.
Ilina Micheva +3 more
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