Results 11 to 20 of about 166,874 (259)
Artificial Cells, Nanomedicine, and Biotechnology, 2019 The objective of this study was to investigate the mechanism underlying miR-21-associated apoptosis in HB. In this study, HB and adjacent tissues were collected from patients with HB.
Lili Liu +6 more
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European Journal of Cancer Supplements, 2015 The efficiency of endocrine therapy for tumors is limited by the development of hormone resistance and progression of tumor cells to hormone-independent phenotype. Among these tumors – breast cancers, for which hormone therapy is one of the most common and effective methods of treatment, but only in cases, when the tumors retain their hormonal ...
S. Semina, M. Krasil’nikov
openaire +2 more sources
Effect of Epigallocatechin-3-Gallate on PMA-Induced MUC5B Expression in Human Airway Epithelial Cells [PDF]
Clinical and Experimental Otorhinolaryngology, 2013 ObjectivesAmong the inflammatory mediators, phorbol 12-myristate 13-acetate (PMA) is associated with the regulation of MUC5B expression in the airway epithelial cells. Epigallocatechin-3-gallate (EGCG) is the major component of green tea extract.
Eun Jung Song +6 more
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Frontiers in Pharmacology, 2020 Intracerebral hemorrhage (ICH) is a disease with a significantly high rate of morbidity, mortality and disability. Inhibition of inflammation is considered a potential strategy for improving the clinical symptoms induced by ICH.
Lu Zhou +7 more
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Cells, 2023 We have recently reported that in G2-phase cells (but not S-phase cells) sustaining low loads of DNA double-strand break (DSBs), ATM and ATR regulate the G2-checkpoint epistatically, with ATR at the output-node, interfacing with the cell cycle through ...
Daxian Luo +4 more
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Molecular mechanism of inhibition of 8-gingerol on proliferation of breast cancer cells
Di-san junyi daxue xuebao, 2019 Objective To investigate the effect of cell cycle on breast cancer cells by 8-gingerol. Methods The cell viability of breast cancer cells MDA-MB-231 and MCF-7 after treated by 8-gingerol at the doses of 0, 10, 20, 30 or 40 μmol/L for 24, 48 or 72 h was ...
YANG Chong, FU Ruoqiu, GAO Ning
doaj +1 more source
LRG-1 promotes pancreatic cancer growth and metastasis via modulation of the EGFR/p38 signaling
Journal of Experimental & Clinical Cancer Research, 2019 Background The abnormal expression of leucine-rich-alpha-2-glycoprotein 1 (LRG-1) is reported to be associated with multiple malignancies, but its role in the progression of pancreatic ductal adenocarcinoma (PDAC) remains to be determined.
Zhi-Bo Xie +4 more
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Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells
Journal of Neuroinflammation, 2011 Background Neuropeptide Y (NPY) is emerging as a modulator of communication between the brain and the immune system. However, in spite of increasing evidence that supports a role for NPY in the modulation of microglial cell responses to inflammatory ...
Ferreira Raquel +6 more
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Peroxiredoxin 3 Inhibits Cardiac Fibrosis in Mice via NOX4-P38 Signalling [PDF]
Cell Journal, 2023 Objective: Peroxiredoxin-3 (Prx-3) is widely acknowledged as an antioxidant that protects against mitochondrialreactive oxygen species. Nonetheless, its role in cardiac fibrosis has not been elucidated. We aim to explore the roleand mechanism of Prx-3 in
Xiaoqi Xiong +9 more
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CHTM1 regulates cancer cell sensitivity to metabolic stress via p38-AIF1 pathway
Journal of Experimental & Clinical Cancer Research, 2019 Background Recently, we have reported the characterization of a novel protein named Coiled-coil Helix Tumor and Metabolism 1 (CHTM1). CHTM1 localizes to both cytosol and mitochondria.
Mansi Babbar +3 more
doaj +1 more source