Results 1 to 10 of about 460,994 (251)

Molecular Mechanisms of Mechanical Stress Response during Chondrogenesis

open access: yesJournal of Biomechanical Science and Engineering, 2009
Muscloskeletal tissues, bone, cartilage, muscles and tendons regulate and support the body's actions and are differentiated from mesenchymal stem cells.
Ichiro TAKAHASHI   +7 more
doaj   +1 more source

Comprehensive Transcriptome and Metabolome Analysis of Hemp (Cannabis Sativa L.) in Soil Under NaCl Stress

open access: yesJournal of Natural Fibers, 2023
Planting economic crops in soil with salt imbalances can improve land use efficiency. Hemp, which can be planted in low-salinity soil, is a crop with a very high economic value. To reveal the salt tolerance mechanism of hemp, the leaves of Longma #3 and #
Ming Zhang   +4 more
doaj   +1 more source

Effects and Potential Mechanism of Zhuyu Pill Against Atherosclerosis: Network Pharmacology and Experimental Validation

open access: yesDrug Design, Development and Therapy, 2023
Yingying Pan,1,* Xianrong Feng,2,* Wei Song,1,* Xin Zhou,1 Zhen Zhou,3 Gaoyang Chen,1 Tao Shen,1 Xiaobo Zhang1 1School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Hospital of ...
Pan Y   +7 more
doaj  

Functional proteomics of patient derived head and neck squamous cell carcinoma cells reveal novel applications of trametinib

open access: yesCancer Biology & Therapy, 2022
In this study, we report a differential response of mitogen-activated protein kinase–kinase (MEK) inhibitor trametinib in 20 head and neck squamous cell carcinoma (HNSCC) patients’ tumor-derived cell cultures.
Myles Vigoda   +14 more
doaj   +1 more source

JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses

open access: yesCells, 2019
Transforming growth factor-β (TGFβ) has both tumor-suppressive and tumor-promoting effects in breast cancer. These functions are partly mediated through Smads, intracellular transcriptional effectors of TGFβ.
Anders Sundqvist   +10 more
doaj   +1 more source

Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation

open access: yesJournal of Inflammation Research, 2022
Jung Lo,1,2 Ching-Chih Liu,3,4 Yueh-Shan Li,3 Po-Yen Lee,3,5 Po-Len Liu,6 Pei-Chang Wu,1,2 Tzu-Chieh Lin,7 Chi-Shuo Chen,8 Chien-Chih Chiu,9 Yu-Hung Lai,3,5,10 Yo-Chen Chang,3,5,10 Hsin-En Wu,3 Yuan-Ru Chen,3 Yu-Kai Huang,3,11 Shu-Pin Huang,1,12– 14 Shu ...
Lo J   +16 more
doaj  

The effect of 8 weeks of interval training combined with the consumption of cineole, linalool, and bourbonene on MAPK/Arc gene expression and learning in rats with Alzheimer’s disease [PDF]

open access: yesJournal of Shahrekord University of Medical Sciences
Background and aims: This research aimed to investigate the effect of 8 weeks of interval training and the use of cineole, linalool, and bourbonene on MAPK/Arc gene expression and learning in Alzheimer’s disease (AD) rats.
Elham Majidi   +3 more
doaj   +1 more source

Effect of Blumeria graminis (Powdery Mildew) on Expression of Genes Involved in Antioxidant Enzymes Pathway in Resistance Reaction of Barley [PDF]

open access: yesپژوهش‌های ژنتیک گیاهی
Barley (Hordeum vulgare L.), one of the first domesticated crops, holds significant agricultural importance and isglobally ranked fourth among crops, following wheat, rice, and maize.
Seyedeh Sanaz Ramezanpour   +2 more
doaj   +1 more source

Metformin alters signaling induced crosstalk and homeostasis in the carcinogenesis paradigm “Epistemology of the origin of cancer”

open access: yes4 open, 2019
The anti-hyperglycemic drug, Metformin, is effective in treating early stages of diabetes and has been associated with a 37% decrease in cancer incidence. While the precise mechanisms for the anti-cancer effects of Metformin remain to be elucidated, this
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Assesmen Program Pelaksanaan Otonomi Pendidikan Karakter di MAPK (Madrasah Aliyah Pr0gram Khusus) Syaikh Zainuddin NW Anjani Lombok Timur NTB

open access: yesPalapa: Jurnal Studi Keislaman dan Ilmu Pendidikan, 2014
Penelitian ini bertujuan untuk mengungkapkan proses pengambilan keputusan, pengelolaan kelembagaan, pengelolaan program, proses belajar mengajar, proses Assesmen, hubungan kerjasama dan partisipasi, sikap kemandirian, keterbukaan, keberlanjutan program ...
Ittihad Ittihad
doaj   +1 more source

Home - About - Disclaimer - Privacy