Results 11 to 20 of about 595,983 (300)
Bone & Joint Research, 2023 Aims: Osteoarthritis (OA) is a prevalent joint disorder with inflammatory response and cartilage deterioration as its main features. Dihydrocaffeic acid (DHCA), a bioactive component extracted from natural plant (gynura bicolor), has demonstrated anti ...
Rui Lu +7 more
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Insidious Onset of Pulmonary Langerhans Cell Histiocytosis During Oncological Follow-Up
Journal of the Belgian Society of Radiology, 2022 Teaching Point: Pulmonary Langerhans cell histiocytosis (PLCH) has to be included in the differential diagnosis of cystic pulmonary lesions on chest computed tomography (CT).
Nico Hustings +2 more
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Journal of Pure and Applied Microbiology, 2021 Computational databases and tools in recent times have been proved to provide an essential aid for anticancer studies in the field of oncology. Molecular docking studies facilitate the structural diversity of plant-derived phytomolecules having ...
Amar Shankar +8 more
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The Winner Takes It All: Auxin–The Main Player during Plant Embryogenesis
Cells, 2020 In plants, the first asymmetrical division of a zygote leads to the formation of two cells with different developmental fates. The establishment of various patterns relies on spatial and temporal gene expression, however the precise mechanism responsible
Konrad Winnicki
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Heat Shock Protein 70 Protects the Heart from Ischemia/Reperfusion Injury through Inhibition of p38 MAPK Signaling. [PDF]
, 2020 BackgroundHeat shock protein 70 (Hsp70) has been shown to exert cardioprotection. Intracellular calcium ([Ca2+]i) overload induced by p38 mitogen-activated protein kinase (p38 MAPK) activation contributes to cardiac ischemia/reperfusion (I/R) injury ...
Chen, Qing-Cai +10 more
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MAPK15 controls mitochondrial fitness and contributes to prevent cellular senescence
Autophagy Reports, 2022 Aberrant production of reactive oxygen species (ROS) from dysfunctional mitochondria leads to oxidative stress and DNA damage, which induces the cellular senescence stress response pathway.
Lorenzo Franci +2 more
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Frontiers in Neurology, 2013 The nature of "toxic" tau in Alzheimer's disease (AD) has been unclear. During pathogenesis, the importance of tau oligomerization vs. tau phosphorylation is controversial and the investigation of both remains critical toward defining the "toxicity" of tau.
Leugers, Chad J. +3 more
openaire +3 more sources
Protein kinases as therapeutic targets to develop anticancer drugs with natural alkaloids
Frontiers in Bioscience-Landmark, 2021 Backgroud: Protein kinases play an important role in cell proliferation, differentiation, mobility and cell cycle arrest etc. These enzymes act as important targets in developing anticancer agents.
Hanlin Ye +10 more
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Reactive oxygen species mediate TNF-α-induced inflammatory response in bone marrow mesenchymal cells [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): It is generally believed that the inflammatory response in bone marrow mesenchymal stem cells (BMSCs) transplantation leads to poor survival and unsatisfactory effects, and is mainly mediated by cytokines, including interleukin-1β (IL-1β ...
Liuzhong Wu, Yaping Pan
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Langerhans Cell Histiocytosis in Adults: Treatment Opportunities of Today
Клиническая онкогематология, 2021 Langerhans cell histiocytosis (LCH) is an extremely rare disease associated with tissue infiltration by pathological cells which are phenotypically similar to normal Langerhans cells.
Vitalii Dmitrievich Latyshev +1 more
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